| Exercise-induced asthma and cardiovascular fitness in asthmatic children. | |
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MedLine Citation:
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PMID: 8711660 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The role of physical training in the management of children with exercise-induced asthma is controversial. A study was undertaken to determine whether a relationship could be found between the occurrence of exercise-induced asthma and the degree of cardiovascular fitness in asthmatic children. METHODS: Twenty eight children aged 6-13 with mild to moderate asthma and dyspnoea during or after physical exercise were tested. All patients had a basal forced expiratory volume in one second (FEV1) of > 80% predicted. Twelve patients were taking corticosteroid maintenance medication by inhalation and 16 were not. Two exercise tests were performed on a treadmill to assess peak oxygen consumption rate (VO2max) and the percentage decrease in FEV1 after exercise. RESULTS: There was no correlation between the VO2max and the percentage decrease in FEV1. Patients not taking steroids showed a greater fall in FEV1 than those receiving corticosteroid medication (mean fall in FEV1 28.7% versus 6.6%). Four of the 12 children treated with steroids and two of the 16 children not taking steroids had a level of cardiovascular fitness lower than the 5th percentile for healthy Dutch children. CONCLUSION: Normal cardiovascular fitness does not prevent exercise-induced asthma. |
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Authors:
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B J Thio; A F Nagelkerke; A G Ketel; B L van Keeken; J E Dankert-Roelse |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Thorax Volume: 51 ISSN: 0040-6376 ISO Abbreviation: Thorax Publication Date: 1996 Feb |
Date Detail:
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Created Date: 1996-09-12 Completed Date: 1996-09-12 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0417353 Medline TA: Thorax Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 207-9 Citation Subset: IM |
Affiliation:
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Department of Paediatric Pulmonogy, Academisch Ziekenhuis Vrije Universiteit, Amsterdam, Netherlands. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Albuterol / therapeutic use Asthma, Exercise-Induced / drug therapy, physiopathology* Bronchodilator Agents / therapeutic use Cardiovascular Physiological Phenomena* Child Exercise Test Female Forced Expiratory Volume Humans Male Oxygen Consumption Physical Fitness* |
| Chemical | |
Reg. No./Substance:
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0/Bronchodilator Agents; 18559-94-9/Albuterol |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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