Document Detail


Exercise-induced acute kidney injury with reversible posterior leukoencephalopathy syndrome.
MedLine Citation:
PMID:  19809784     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a case of a 17-year-old boy suffering from severe loin pain and oliguric acute kidney injury after strenuous exercise, with slightly elevated serum myoglobin and creatinine phosphokinase. Exercise-induced acute kidney injury (AKI) was diagnosed. We started intermittent hemodialysis thrice a week from the admission day. Four days later, he temporally lost consciousness, followed by visual agnosia and general clonic seizure. T2-weighted brain magnetic resonance images (MRI) showed multiple areas of increased signal intensity in the subcortical white matter, predominantly in the cerebrum of the posterior and parietal lobes and in the cerebellum. Clinical symptoms improved without sequelae. Follow-up MRI 1 month later showed complete resolution of the signals, and he was diagnosed with reversible posterior leukoencephalopathy syndrome (RPLS). This is the first reported case of exercise-induced AKI associated with RPLS. Vasoconstriction and endothelial dysfunction are considered as the common etiology of these diseases.
Authors:
Tomonori Kimura; Ken-ichiro Iio; Enyu Imai; Hiromi Rakugi; Yoshitaka Isaka; Terumasa Hayashi
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-10-07
Journal Detail:
Title:  Clinical and experimental nephrology     Volume:  14     ISSN:  1437-7799     ISO Abbreviation:  Clin. Exp. Nephrol.     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-04-05     Completed Date:  2010-06-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9709923     Medline TA:  Clin Exp Nephrol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  173-5     Citation Subset:  IM    
Affiliation:
Department of Geriatric Medicine and Nephrology, Osaka University School of Medicine, Suita, Osaka 585-0871, Japan. t-kimura@kid.med.osaka-u.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Exercise*
Humans
Kidney / injuries*
Magnetic Resonance Imaging
Male
Pain / etiology
Posterior Leukoencephalopathy Syndrome / etiology*
Renal Dialysis
Uric Acid
Chemical
Reg. No./Substance:
69-93-2/Uric Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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