Document Detail

Exercise-induced ST-segment depression in inferior leads during treadmill exercise testing and coronary artery disease.
MedLine Citation:
PMID:  19176254     Owner:  NLM     Status:  In-Data-Review    
The exercise electrocardiogram is a commonly used non-invasive and inexpensive method for detection of electrocardiogram (ECG) changes secondary to myocardial ischemia. Reversible ST-segment depression is the characteristic finding associated with exercise-induced, demand-driven ischemia in patients with significant coronary obstruction but no flow limitation at rest. The exercise-induced ST-segment depression in inferior leads has been questioned and it has been reported that lead V5 alone consistently outperforms the inferior leads and the combination of lead V5 with II, because lead II has a high false-positive rate. A review of the 12-lead visual electrocardiographic interpretations confirmed that changes isolated to the inferior leads were rare in patients, who had no diagnostic Q waves. Considering the sum of ST-segment depression or the most depression in the three leads representing the three main areas of the myocardium (II, V2, and V5) did not improve the diagnostic capacity of the test. A case is presented to illustrate how in a patient, the ST-segment depression in inferior leads during exercise testing is related with significant coronary artery disease. We present a case of exercise-induced ST-segment depression in inferior leads in a 52 year-old Italian man. This experience demonstrates that ST-segment depression in inferior leads during the exercise testing can have a diagnostic significance.
Salvatore Patanè; Filippo Marte; Giuseppe Dattilo; Rosario Grassi; Francesco Patanè
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Publication Detail:
Type:  Journal Article     Date:  2009-01-26
Journal Detail:
Title:  International journal of cardiology     Volume:  145     ISSN:  1874-1754     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-12-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  e88-91     Citation Subset:  IM    
Copyright Information:
Copyright © 2008 Elsevier Ireland Ltd. All rights reserved.
Cardiologia Nuovo Presidio Ospedaliero Cutroni Zodda-Barcellona P.d.G(Me) AUSL5 Messina, Via Cattafi 98051, Barcellona Pozzo di Gotto, Messina, Italy.
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