Document Detail

Exercise and heart disease: from athletes and arrhythmias to hypertrophic cardiomyopathy and congenital heart disease.
MedLine Citation:
PMID:  23259479     Owner:  NLM     Status:  In-Data-Review    
The beneficial effects of regular physical activity on cardiovascular health are well established, with convincing evidence of improvements in blood pressure, lipid profile and overall mortality. Conversely, individuals with pre-existing congenital, inherited or acquired heart conditions may experience functional cardiac deterioration or sudden death during even moderate exertion. Exclusion from high-level sporting activity may be mandated in some cases, and pre-participation screening of competitive athletes plays an important role in the identification of such individuals. The issue of screening is complicated by the fact that physiological cardiovascular adaptation in healthy athletes, including modest left ventricular hypertrophy and biventricular cavity dilatation, may create a diagnostic overlap with pathological conditions such as hypertrophic cardiomyopathy. Furthermore, much interest has focused recently on the possibility of irreversible cardiac remodeling in a proportion of veteran endurance athletes, with the potential for arrhythmogenesis and adverse cardiac events.
Abbas Zaidi; Sanjay Sharma
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Future cardiology     Volume:  9     ISSN:  1744-8298     ISO Abbreviation:  Future Cardiol     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2012-12-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101239345     Medline TA:  Future Cardiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  119-36     Citation Subset:  IM    
Department of Cardiovascular Sciences, St George's, University of London, Cranmer Terrace, London SW17 0RE, UK.
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