| Exercise dose and quality of life: a randomized controlled trial. | |
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MedLine Citation:
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PMID: 19204218 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Improved quality of life (QOL) is a purported benefit of exercise, but few randomized controlled trials and no dose-response trials have been conducted to examine this assertion. METHODS: The effect of 50%, 100%, and 150% of the physical activity recommendation on QOL was examined in a 6-month randomized controlled trial. Participants were 430 sedentary postmenopausal women (body mass index range, 25.0-43.0 [calculated as weight in kilograms divided by height in meters squared]) with elevated systolic blood pressure randomized to a nonexercise control group (n = 92) or 1 of 3 exercise groups: exercise energy expenditure of 4 (n = 147), 8 (n = 96), or 12 (n = 95) kilocalories per kilogram of body weight per week. Eight aspects of physical and mental QOL were measured at baseline and month 6 with the use of the Medical Outcomes Study 36-Item Short Form Health Survey. RESULTS: Change in all mental and physical aspects of QOL, except bodily pain, was dose dependent (trend analyses were significant, and exercise dose was a significant predictor of QOL change; P < .05). Higher doses of exercise were associated with larger improvements in mental and physical aspects of QOL. Controlling for weight change did not attenuate the exercise-QOL association. CONCLUSION: Exercise-induced QOL improvements were dose dependent and independent of weight change. |
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Authors:
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Corby K Martin; Timothy S Church; Angela M Thompson; Conrad P Earnest; Steven N Blair |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: Archives of internal medicine Volume: 169 ISSN: 1538-3679 ISO Abbreviation: Arch. Intern. Med. Publication Date: 2009 Feb |
Date Detail:
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Created Date: 2009-02-10 Completed Date: 2009-03-03 Revised Date: 2010-12-03 |
Medline Journal Info:
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Nlm Unique ID: 0372440 Medline TA: Arch Intern Med Country: United States |
Other Details:
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Languages: eng Pagination: 269-78 Citation Subset: AIM; IM |
Affiliation:
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Pennington Biomedical Research Center, Louisiana State University System, 6400 Perkins Road, Baton Rouge, LA 70808, USA. Martin@pbrc.edu |
| Data Bank Information | |
Bank Name/Acc. No.:
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ClinicalTrials.gov/NCT00011193 |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Antidepressive Agents / therapeutic use Body Mass Index Depression / drug therapy, epidemiology Employment Energy Metabolism Exercise* Female Health Status Humans Hypertension / epidemiology Mental Health Middle Aged Physical Fitness Postmenopause Quality of Life* Systole Weight Loss |
| Grant Support | |
ID/Acronym/Agency:
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1K23 DK 068052/DK/NIDDK NIH HHS; HL 66262/HL/NHLBI NIH HHS; K23 DK068052-01A2/DK/NIDDK NIH HHS; R01 HL066262-01/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Antidepressive Agents |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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