Document Detail

Exercise capacity before and after an 8-week multidisciplinary inpatient rehabilitation program in lung cancer patients: a pilot study.
MedLine Citation:
PMID:  16529844     Owner:  NLM     Status:  MEDLINE    
Although lung cancer is a highly prevalent type of cancer, the effects of an inpatient multidisciplinary rehabilitation program on pulmonary function and exercise capacity have never been studied in these patients. Pulmonary function, 6-min walking distance and peak exercise capacity of 10 patients with a severely impaired pulmonary function following treatment of lung cancer were assessed in this pilot study before and after an 8-week inpatient multidisciplinary rehabilitation program. At baseline, patients had a restrictive pulmonary function and an apparent exercise intolerance (median 6-min walking distance: 63.6% predicted; median peak cycling load: 58.5% predicted). Despite the lack of change in median pulmonary function [FEV1: -0.01L, p = 0.5469], functional exercise capacity [145 m; 43.2% of the initial values, p=0.0020] and peak exercise capacity [26 W; 34.4% of the initial values, p = 0.0078] improved significantly compared to baseline. Future trials have to corroborate the present findings. Nevertheless, patients with lung cancer have a clear indication to start a comprehensive rehabilitation program following intensive treatment of their disease. In fact, based on the results of the present pilot study it appears that these patients are good candidates for pulmonary rehabilitation programs.
Martijn A Spruit; Paul P Janssen; Sonja C P Willemsen; Monique M H Hochstenbag; Emiel F M Wouters
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article     Date:  2006-03-09
Journal Detail:
Title:  Lung cancer (Amsterdam, Netherlands)     Volume:  52     ISSN:  0169-5002     ISO Abbreviation:  Lung Cancer     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-04-17     Completed Date:  2006-09-21     Revised Date:  2007-07-19    
Medline Journal Info:
Nlm Unique ID:  8800805     Medline TA:  Lung Cancer     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  257-60     Citation Subset:  IM    
Department of Program Development & Education, PD&E, Centre of Integrated Rehabilitation and Organ failure, CIRO, P.O. Box 4080, 6080AB Haelen, the Netherlands.
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MeSH Terms
Exercise Therapy / methods*
Exercise Tolerance / physiology*
Follow-Up Studies
Forced Expiratory Flow Rates / physiology
Lung Neoplasms / physiopathology,  rehabilitation*
Middle Aged
Pilot Projects
Respiratory Function Tests
Treatment Outcome
Walking / physiology
Comment In:
Lung Cancer. 2007 Jul;57(1):118-9   [PMID:  17475363 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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