Document Detail

Exercise capacity and 24-h blood pressure in prehypertensive men and women.
MedLine Citation:
PMID:  16500509     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Prehypertensive individuals are at increased risk for developing hypertension and cardiovascular disease compared to those with normal blood pressure (BP). Physically active, normotensive individuals are also at lower risk for developing hypertension than sedentary individuals. We assessed the relationship between fitness and 24-h ambulatory BP in prehypertensive men and women. METHODS: We assessed exercise capacity and 24-h BP in 407 men (age 51 +/- 11 years) and 243 women (age 54 +/-10 years) with resting systolic BP 120 to 139 mm Hg and diastolic BP of 80 to 89 mm Hg, defined as prehypertension. Fitness categories (low, moderate, and high) were established according to exercise time and age. RESULTS: Multiple regression analysis revealed that fitness status was inversely associated with ambulatory BP in both genders (P < .001). After adjusting for various confounders, individuals in the lowest fitness category had significantly higher 24-h, daytime, and night-time BP than those in the moderate and high fitness categories. For men, differences between low and moderate fitness categories were 6/4 mm Hg, 8/4 mm Hg, and 7/3 mm Hg for 24-h, daytime, and night-time BP, respectively (P < .05). For women, the differences were 8/5 mm Hg, 9/5 mm Hg, and 8/7 mm Hg for 24-h, daytime, and night-time BP, respectively. Similar differences were evident in both genders between low and high fitness category (P < .05). CONCLUSIONS: Moderate physical activity promotes lower BP during a 24-h period in prehypertensive men and women. The risk for developing hypertension is likely to be lowered if moderate intensity physical activity in this vulnerable population is encouraged.
Peter Kokkinos; Andreas Pittaras; Athanasios Manolis; Demosthenes Panagiotakos; Puneet Narayan; Demitra Manjoros; Richard L Amdur; Steven Singh
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of hypertension     Volume:  19     ISSN:  0895-7061     ISO Abbreviation:  Am. J. Hypertens.     Publication Date:  2006 Mar 
Date Detail:
Created Date:  2006-02-27     Completed Date:  2006-05-03     Revised Date:  2009-02-24    
Medline Journal Info:
Nlm Unique ID:  8803676     Medline TA:  Am J Hypertens     Country:  United States    
Other Details:
Languages:  eng     Pagination:  251-8     Citation Subset:  IM    
Veterans Affairs Medical Center/Cardiology Division, Washington, DC; Georgetown University Medical Center, Washington, DC, USA.
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MeSH Terms
Blood Pressure / physiology*
Blood Pressure Monitoring, Ambulatory
Exercise Tolerance / physiology
Hypertension / physiopathology,  prevention & control
Middle Aged
Physical Fitness / physiology*
Regression Analysis
Sex Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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