Document Detail

Exercise can prevent and even reverse adverse effects of androgen suppression treatment in men with prostate cancer.
MedLine Citation:
PMID:  17486110     Owner:  NLM     Status:  MEDLINE    
Side effects accompanying androgen deprivation therapy (ADT), including sarcopenia, loss of bone mass and reduction in muscle strength, can compromise physical function, particularly in older patients. Exercise, specifically resistance training, may be an effective and cost-efficient strategy to limit or even reverse some of these adverse effects during and following therapy. In this review, we discuss common morphological and physiological ADT-related side effects or 'Androgen Deprivation and Sarcopenia-Related Disorders' and the existing clinical trials incorporating physical exercise in prostate cancer patients receiving active therapy. Further, training concepts and guidelines are provided for prescribing resistance exercise programs for this population.
D A Galvão; D R Taaffe; N Spry; R U Newton
Publication Detail:
Type:  Journal Article; Review     Date:  2007-05-08
Journal Detail:
Title:  Prostate cancer and prostatic diseases     Volume:  10     ISSN:  1476-5608     ISO Abbreviation:  Prostate Cancer Prostatic Dis.     Publication Date:  2007  
Date Detail:
Created Date:  2007-11-30     Completed Date:  2008-05-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9815755     Medline TA:  Prostate Cancer Prostatic Dis     Country:  England    
Other Details:
Languages:  eng     Pagination:  340-6     Citation Subset:  IM    
Vario Health Institute, School of Exercise, Biomedical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia.
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MeSH Terms
Androgen Antagonists / adverse effects*,  therapeutic use
Exercise Therapy*
Musculoskeletal Diseases / chemically induced,  therapy*
Prostatic Neoplasms / complications,  drug therapy*
Treatment Outcome
Reg. No./Substance:
0/Androgen Antagonists

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