| Exercise can prevent and even reverse adverse effects of androgen suppression treatment in men with prostate cancer. | |
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MedLine Citation:
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PMID: 17486110 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Side effects accompanying androgen deprivation therapy (ADT), including sarcopenia, loss of bone mass and reduction in muscle strength, can compromise physical function, particularly in older patients. Exercise, specifically resistance training, may be an effective and cost-efficient strategy to limit or even reverse some of these adverse effects during and following therapy. In this review, we discuss common morphological and physiological ADT-related side effects or 'Androgen Deprivation and Sarcopenia-Related Disorders' and the existing clinical trials incorporating physical exercise in prostate cancer patients receiving active therapy. Further, training concepts and guidelines are provided for prescribing resistance exercise programs for this population. |
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Authors:
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D A Galvão; D R Taaffe; N Spry; R U Newton |
Publication Detail:
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Type: Journal Article; Review Date: 2007-05-08 |
Journal Detail:
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Title: Prostate cancer and prostatic diseases Volume: 10 ISSN: 1476-5608 ISO Abbreviation: Prostate Cancer Prostatic Dis. Publication Date: 2007 |
Date Detail:
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Created Date: 2007-11-30 Completed Date: 2008-05-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9815755 Medline TA: Prostate Cancer Prostatic Dis Country: England |
Other Details:
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Languages: eng Pagination: 340-6 Citation Subset: IM |
Affiliation:
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Vario Health Institute, School of Exercise, Biomedical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia. d.galvao@ecu.edu.au |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Androgen Antagonists
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adverse effects*,
therapeutic use Exercise Therapy* Humans Male Musculoskeletal Diseases / chemically induced, therapy* Prostatic Neoplasms / complications, drug therapy* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Androgen Antagonists |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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