Document Detail


Exercise is brain food: the effects of physical activity on cognitive function.
MedLine Citation:
PMID:  18781504     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This commentary reviews selected biomedical and clinical research examining the relationship between physical exercise and cognitive function especially in youth with disability. Youth with physical disability may not benefit from the effects of exercise on cardiovascular fitness and brain health since they are less active than their non-disabled peers. In animal models, physical activity enhances memory and learning, promotes neurogenesis and protects the nervous system from injury and neurodegenerative disease. Neurotrophins, endogenous proteins that support brain plasticity likely mediate the beneficial effects of exercise on the brain. In clinical studies, exercise increases brain volume in areas implicated in executive processing, improves cognition in children with cerebral palsy and enhances phonemic skill in school children with reading difficulty. Studies examining the intensity of exercise required to optimize neurotrophins suggest that moderation is important. Sustained increases in neurotrophin levels occur with prolonged low intensity exercise, while higher intensity exercise, in a rat model of brain injury, elevates the stress hormone, corticosterone. Clearly, moderate physical activity is important for youth whose brains are highly plastic and perhaps even more critical for young people with physical disability.
Authors:
Michelle Ploughman
Related Documents :
22911454 - Identification of exercise capacity qtl using association mapping in inbred mice.
3782724 - Testosterone application influences sympathetic activity of intracardiac nerves in non-...
14652494 - Pgc-1alpha genotype modifies the association of volitional energy expenditure with [ov0...
11543114 - Effect of physical fitness and training on physiological responses to hypogravity.
10148014 - A review of the functional electrical stimulation equipment market.
18093894 - Evaluation of a new strategy to modulate skeletal development in thoroughbred performan...
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Developmental neurorehabilitation     Volume:  11     ISSN:  1751-8431     ISO Abbreviation:  Dev Neurorehabil     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2008-09-10     Completed Date:  2008-12-29     Revised Date:  2009-12-18    
Medline Journal Info:
Nlm Unique ID:  101304394     Medline TA:  Dev Neurorehabil     Country:  England    
Other Details:
Languages:  eng     Pagination:  236-40     Citation Subset:  IM    
Affiliation:
Clinical Research, Rehabilitation Program, Eastern Health Authority, St John's, Newfoundland and Labrador, Canada. mploughm@mun.ca
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Brain / metabolism*,  physiology
Cognition / physiology*
Exercise / physiology*
Female
Humans
Male
Motor Activity / physiology
Nerve Degeneration / prevention & control*
Nerve Growth Factors / metabolism
Nervous System Diseases / pathology,  prevention & control*
Neurogenesis / physiology
Prognosis
Randomized Controlled Trials as Topic
Sensitivity and Specificity
Chemical
Reg. No./Substance:
0/Nerve Growth Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Development and validation of the Paediatric Care and Needs Scale (PCANS) for assessing support need...
Next Document:  EHDI Africa: advocating for infants with hearing loss in Africa.