Document Detail

Exercise and bone mineral density in men: a meta-analysis of randomized controlled trials.
MedLine Citation:
PMID:  23219948     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Use the meta-analytic approach to examine the effects of ground and/or joint reaction force exercise on femoral neck (FN) and lumbar spine (LS) bone mineral density (BMD) in men.
METHODS: Randomized controlled exercise trials ≥ 24 weeks were included. Standardized effect sizes (g) were calculated and pooled using random-effects models, z-score alpha values and 95% confidence intervals (CI). Heterogeneity was examined using Q and I(2). Statistical significance was set at a two-tailed alpha value (p) of ≤ 0.05 and a trend at >0.05 to ≤ 0.10.
RESULTS: A moderate and statistically significant improvement was found at the FN (3 g's, 187 participants, g=0.583, 95% CI=0.031, 1.135, p=0.04, Q=5.6, p=0.06, I(2)=64%) while a small trend was observed at the LS (5 g's, 275 participants, g=0.190, 95% CI=-0.036, 0.416, p=0.10, Q=3.0, p=0.55, I(2)=0%). Results were sensitive to influence analysis as well as collapsing multiple groups from the same studies so that only one g represented each study.
CONCLUSIONS: There is currently insufficient evidence to recommend ground and/or joint reaction force exercise for improving and/or maintaining FN and LS BMD in men. Additional well-designed randomized controlled trials are needed before any final recommendations can be formulated.
G A Kelley; K S Kelley; W M Kohrt
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Publication Detail:
Type:  Journal Article; Meta-Analysis; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2012-12-04
Journal Detail:
Title:  Bone     Volume:  53     ISSN:  1873-2763     ISO Abbreviation:  Bone     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-01-21     Completed Date:  2013-08-16     Revised Date:  2013-09-09    
Medline Journal Info:
Nlm Unique ID:  8504048     Medline TA:  Bone     Country:  United States    
Other Details:
Languages:  eng     Pagination:  103-11     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
School of Public Health, Department of Biostatistics, Robert C. Byrd Health Sciences Center, West Virginia University, PO Box 9190, Morgantown, WV 26506-9190, USA.
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MeSH Terms
Bone Density*
Femur Neck
Lumbar Vertebrae
Middle Aged
Randomized Controlled Trials as Topic*
Erratum In:
Bone. 2013 Sep;56(1):30

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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