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Exercise and bone mineral density in men: A meta-analysis of randomized controlled trials.
MedLine Citation:
PMID:  23219948     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE: Use the meta-analytic approach to examine the effects of ground and/or joint reaction force exercise on femoral neck (FN) and lumbar spine (LS) bone mineral density (BMD) in men. METHODS: Randomized controlled exercise trials ≥24weeks were included. Standardized effect sizes (g) were calculated and pooled using random-effects models, z-score alpha values and 95% confidence intervals (CI). Heterogeneity was examined using Q and I(2). Statistical significance was set at a two-tailed alpha value (p) of ≤0.05 and a trend at >0.05 to ≤0.10. RESULTS: A moderate and statistically significant improvement was found at the FN (3 g's, 187 participants, g=0.583, 95% CI=0.031, 1.135, p=0.04, Q=5.6, p=0.06, I(2)=64%) while a small trend was observed at the LS (5 g's, 275 participants, g=0.190, 95% CI=-0.036, 0.416, p=0.10, Q=3.0, p=0.55, I(2)=0%). Results were sensitive to influence analysis as well as collapsing multiple groups from the same studies so that only one g represented each study. CONCLUSIONS: There is currently insufficient evidence to recommend ground and/or joint reaction force exercise for improving and/or maintaining FN and LS BMD in men. Additional well-designed randomized controlled trials are needed before any final recommendations can be formulated.
Authors:
G A Kelley; K S Kelley; W M Kohrt
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-4
Journal Detail:
Title:  Bone     Volume:  -     ISSN:  1873-2763     ISO Abbreviation:  Bone     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8504048     Medline TA:  Bone     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012. Published by Elsevier Inc.
Affiliation:
School of Public Health, Department of Biostatistics, Robert C. Byrd Health Sciences Center, West Virginia University, PO Box 9190, Morgantown, WV 26506-9190, USA. Electronic address: gkelley@hsc.wvu.edu.
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