Document Detail


Exercise body surface potential mapping in single and multiple coronary artery disease.
MedLine Citation:
PMID:  2347218     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Body surface ST integral maps were recorded in 36 coronary artery disease (CAD) patients at: rest; peak, angina-limited exercise; and, 1 and 5 min of recovery. They were compared to maps of 15 CAD patients who exercised to fatigue, without angina, and eight normal subjects. Peak exercise heart rates were similar (NS) in all groups. With exercise angina, patients with two and three vessel CAD had significantly (p less than 0.05) greater decrease in the body surface sum of ST integral values than patients with single vessel CAD. CAD patients with exercise fatigue, in the absence of angina, had decreased ST integrals similar (NS) to patients with single vessel CAD who manifested angina and the normal control subjects. There was, however, considerable overlap among individuals; some patients with single vessel CAD had as much exercise ST integral decrease as patients with three vessel CAD. All CAD patients had persistent ST integral decreases at 5 min of recovery and there was a direct correlation of the recovery and peak exercise ST changes. Exercise ST changes correlated, as well, with quantitative CAD angiographic scores, but not with thallium perfusion scores. These data suggest exercise ST integral body surface mapping allows quantitation of myocardium at ischemic risk in patients with CAD, irrespective of the presence or absence of ischemic symptoms during exercise. A major potential application of this technique is selection of CAD therapy guided by quantitative assessment of ischemic myocardial risk.
Authors:
T J Montague; F X Witkowski; R M Miller; D E Johnstone; R B MacKenzie; C A Spencer; B M Horacek
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Chest     Volume:  97     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1990 Jun 
Date Detail:
Created Date:  1990-07-09     Completed Date:  1990-07-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1333-42     Citation Subset:  AIM; IM    
Affiliation:
Heritage Cardiovascular Research Group, University of Alberta, Edmonton, Canada.
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MeSH Terms
Descriptor/Qualifier:
Adult
Coronary Angiography
Coronary Disease / diagnosis*
Electrocardiography / methods*
Exercise Test
Female
Heart / radionuclide imaging
Heart Rate / physiology
Humans
Male
Middle Aged
Risk Factors
Thallium Radioisotopes / diagnostic use
Chemical
Reg. No./Substance:
0/Thallium Radioisotopes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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