| Exercise blood pressure response is related to left ventricular mass. | |
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MedLine Citation:
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PMID: 12756406 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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An exaggerated SBP response to exercise has been associated with increased left ventricular (LV) mass in some but not all studies. A total of 43 women and 34 men, aged 55-75 years, without evidence of cardiovascular disease, with a mean resting BP of 142+/-9/77+/-8 mmHg had their BP measured at rest and during maximal treadmill exercise. LV mass was measured using magnetic resonance imaging. LV mass was adjusted for lean body mass, which was assessed by dual energy X-ray absorptiometry. LV mass was within the normal range for the majority of the subjects. Among the resting and exercise BP indices, maximal SBP was the strongest correlate of LV mass (r=0.41, P<0.05). In multivariate analysis, maximal SBP was independently associated with LV mass after adjustment for lean body mass and gender, explaining 3% of the variance (P<0.05). Maximal exercise SBP is a modest but still independent predictor of LV mass in older persons with normal LV mass. These results raise the possibility that the SBP response to maximal exercise is an early marker of LV hypertrophy. |
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Authors:
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J Sung; P Ouyang; H A Silber; A C Bacher; K L Turner; J R DeRegis; P S Hees; E P Shapiro; K J Stewart |
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Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Journal of human hypertension Volume: 17 ISSN: 0950-9240 ISO Abbreviation: J Hum Hypertens Publication Date: 2003 May |
Date Detail:
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Created Date: 2003-05-20 Completed Date: 2003-09-04 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8811625 Medline TA: J Hum Hypertens Country: England |
Other Details:
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Languages: eng Pagination: 333-8 Citation Subset: IM |
Affiliation:
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Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Blood Pressure / physiology* Body Composition / physiology Body Mass Index Diastole / physiology Exercise / physiology* Exercise Test Female Heart Rate / physiology Heart Ventricles / anatomy & histology, physiopathology Humans Hypertension / physiopathology Hypertrophy, Left Ventricular / physiopathology Male Middle Aged Multivariate Analysis Organ Size Oxygen Consumption / physiology Predictive Value of Tests Sex Factors Statistics as Topic Systole / physiology |
| Grant Support | |
ID/Acronym/Agency:
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HL59164/HL/NHLBI NIH HHS; M01RR02715/RR/NCRR NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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