Document Detail

Exercise blood pressure response is related to left ventricular mass.
MedLine Citation:
PMID:  12756406     Owner:  NLM     Status:  MEDLINE    
An exaggerated SBP response to exercise has been associated with increased left ventricular (LV) mass in some but not all studies. A total of 43 women and 34 men, aged 55-75 years, without evidence of cardiovascular disease, with a mean resting BP of 142+/-9/77+/-8 mmHg had their BP measured at rest and during maximal treadmill exercise. LV mass was measured using magnetic resonance imaging. LV mass was adjusted for lean body mass, which was assessed by dual energy X-ray absorptiometry. LV mass was within the normal range for the majority of the subjects. Among the resting and exercise BP indices, maximal SBP was the strongest correlate of LV mass (r=0.41, P<0.05). In multivariate analysis, maximal SBP was independently associated with LV mass after adjustment for lean body mass and gender, explaining 3% of the variance (P<0.05). Maximal exercise SBP is a modest but still independent predictor of LV mass in older persons with normal LV mass. These results raise the possibility that the SBP response to maximal exercise is an early marker of LV hypertrophy.
J Sung; P Ouyang; H A Silber; A C Bacher; K L Turner; J R DeRegis; P S Hees; E P Shapiro; K J Stewart
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of human hypertension     Volume:  17     ISSN:  0950-9240     ISO Abbreviation:  J Hum Hypertens     Publication Date:  2003 May 
Date Detail:
Created Date:  2003-05-20     Completed Date:  2003-09-04     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8811625     Medline TA:  J Hum Hypertens     Country:  England    
Other Details:
Languages:  eng     Pagination:  333-8     Citation Subset:  IM    
Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA.
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MeSH Terms
Blood Pressure / physiology*
Body Composition / physiology
Body Mass Index
Diastole / physiology
Exercise / physiology*
Exercise Test
Heart Rate / physiology
Heart Ventricles / anatomy & histology,  physiopathology
Hypertension / physiopathology
Hypertrophy, Left Ventricular / physiopathology
Middle Aged
Multivariate Analysis
Organ Size
Oxygen Consumption / physiology
Predictive Value of Tests
Sex Factors
Statistics as Topic
Systole / physiology
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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