Document Detail


Exercise and associated dietary extremes impact on gut microbial diversity.
MedLine Citation:
PMID:  25021423     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE: The commensal microbiota, host immunity and metabolism participate in a signalling network, with diet influencing each component of this triad. In addition to diet, many elements of a modern lifestyle influence the gut microbiota but the degree to which exercise affects this population is unclear. Therefore, we explored exercise and diet for their impact on the gut microbiota.
DESIGN: Since extremes of exercise often accompany extremes of diet, we addressed the issue by studying professional athletes from an international rugby union squad. Two groups were included to control for physical size, age and gender. Compositional analysis of the microbiota was explored by 16S rRNA amplicon sequencing. Each participant completed a detailed food frequency questionnaire.
RESULTS: As expected, athletes and controls differed significantly with respect to plasma creatine kinase (a marker of extreme exercise), and inflammatory and metabolic markers. More importantly, athletes had a higher diversity of gut micro-organisms, representing 22 distinct phyla, which in turn positively correlated with protein consumption and creatine kinase.
CONCLUSIONS: The results provide evidence for a beneficial impact of exercise on gut microbiota diversity but also indicate that the relationship is complex and is related to accompanying dietary extremes.
Authors:
Siobhan F Clarke; Eileen F Murphy; Orla O'Sullivan; Alice J Lucey; Margaret Humphreys; Aileen Hogan; Paula Hayes; Maeve O'Reilly; Ian B Jeffery; Ruth Wood-Martin; David M Kerins; Eamonn Quigley; R Paul Ross; Paul W O'Toole; Michael G Molloy; Eanna Falvey; Fergus Shanahan; Paul D Cotter
Related Documents :
8789563 - Plasma sulpho-conjugated catecholamine dynamics up to 8 h after 60-min exercise at 50% ...
3512263 - Plasma renin and aldosterone changes during twenty minutes' moderate exercise. influenc...
1445163 - Seasonal effects on human physiological adaptation factors, thermotolerance and plasma ...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-6-9
Journal Detail:
Title:  Gut     Volume:  -     ISSN:  1468-3288     ISO Abbreviation:  Gut     Publication Date:  2014 Jun 
Date Detail:
Created Date:  2014-7-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985108R     Medline TA:  Gut     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Integration of tumour and viral genomic characterisations in HBV-related hepatocellular carcinomas.
Next Document:  Effect of antidepressant drug on semicarbazide-sensitive amine oxidase (SSAO) in dog brain.