Document Detail


Exercise as a model to study redox homeostasis in blood: the effect of protocol and sampling point.
MedLine Citation:
PMID:  22288504     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Twenty males ran either on a level treadmill (nonmuscle-damaging condition) or on a downhill treadmill (muscle-damaging condition). Blood and urine samples were collected before and after exercise (immediately after, 1h, 4h, 24h, 48h, and 96h). The following assays were performed: F(2)-isoprostanes in urine, protein carbonyls in plasma, glutathione, superoxide dismutase, glutathione peroxidase, and catalase in erythrocytes. The main finding was that monophasic redox responses were detected after nonmuscle-damaging exercise compared to the biphasic responses detected after muscle-damaging exercise. Based on these findings, muscle-damaging exercise may be a more appropriate experimental model to induce physiological oxidative stress.
Authors:
Michalis G Nikolaidis; Antonios Kyparos; Konstantina Dipla; Andreas Zafeiridis; Michalis Sambanis; Gerasimos V Grivas; Vassilis Paschalis; Anastasios A Theodorou; Stavros Papadopoulos; Chrysoula Spanou; Ioannis S Vrabas
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals     Volume:  17     ISSN:  1366-5804     ISO Abbreviation:  Biomarkers     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-01-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9606000     Medline TA:  Biomarkers     Country:  England    
Other Details:
Languages:  eng     Pagination:  28-35     Citation Subset:  IM    
Affiliation:
Exercise Physiology and Biochemistry Laboratory, Department of Physical Education and Sport Sciences at Serres, Aristotle University of Thessaloniki , Serres , Greece.
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