Document Detail

Exercise and allergic diseases.
MedLine Citation:
PMID:  15285469     Owner:  NLM     Status:  MEDLINE    
The aim of this study was to compare exercise-induced bronchial reaction between healthy control subjects and subjects with allergic rhinitis (AR) and allergic asthma (AA). It included 16 controls, 16 subjects with AR and 19 subjects with AA. A skin prick test, pulmonary function test, histamine challenge test and exercise challenge test (ECT) were performed in all subjects. Bronchial reaction to exercise was expressed as the fall index FEV1 (%), AUC(0-30) (min x %), and fall index FEF(25-75) (%). After ECT, subjects with AA had a significantly greater bronchial reaction to exercise than subjects with AR and controls (respective fall index FEV1 8.4, 2.9, and 2.4%, P=0.0083; AUC(0-30) 127.7, 29.6, and 33.1 min x %, P=0.025; and fall index FEF(25-75) 14.6, 0.06, and 1.9%, P<0.001). No difference was found between subjects with AR and controls. In conclusion, ECT induced a significantly greater bronchial reaction in patients with AA and bronchial hyperreactivity to histamine than in patients with AR and bronchial normoreactivity to histamine and controls. This difference was not found between subjects with AR and controls.
Tajana Klepac-Pulanić; Jelena Macan; Davor Plavec; Bozica Kanceljak-Macan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Arhiv za higijenu rada i toksikologiju     Volume:  55     ISSN:  0004-1254     ISO Abbreviation:  Arh Hig Rada Toksikol     Publication Date:  2004 Jun 
Date Detail:
Created Date:  2004-08-02     Completed Date:  2004-08-31     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0373100     Medline TA:  Arh Hig Rada Toksikol     Country:  Croatia    
Other Details:
Languages:  eng     Pagination:  197-204     Citation Subset:  IM    
Institute for Medical Research and Occupational Health, Zagreb, Croatia.
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MeSH Terms
Asthma / physiopathology*
Bronchial Provocation Tests
Middle Aged
Respiratory Mechanics
Rhinitis, Allergic, Perennial / physiopathology*
Rhinitis, Allergic, Seasonal / physiopathology*

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