Document Detail

Exercise ability after Mustard's operation.
MedLine Citation:
PMID:  2400223     Owner:  NLM     Status:  MEDLINE    
Twenty children who were well six to 12 years after undergoing Mustard's operation for transposition of the great arteries were studied. Each child performed a graded maximal treadmill test with measurements of gas exchange and oxygen saturation, and had electrocardiography carried out. Nineteen were also catheterised, and oxygen consumption was measured so that pulmonary and systemic flow could be calculated. Compared with 20 age and size matched controls, seven of the patients had normal exercise tolerance (as judged by a maximal oxygen consumption of greater than 40 ml/kg/min), 10 showed a moderate reduction (30-39 ml/kg/min), and three were more seriously limited. None of the patients with normal exercise tolerance had obstruction of venous return but six of those with mild impairment of exercise ability had partial or complete obstruction of one or both of the vena cavas. More severe limitation was associated with pulmonary vascular disease and fixed ventricular outflow tract obstruction. Formal exercise testing of apparently well children who have undergone Mustard's operation identifies those with haemodynamic abnormalities that may require intervention.
J J Bowyer; C M Busst; J A Till; C Lincoln; E A Shinebourne
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of disease in childhood     Volume:  65     ISSN:  1468-2044     ISO Abbreviation:  Arch. Dis. Child.     Publication Date:  1990 Aug 
Date Detail:
Created Date:  1990-10-18     Completed Date:  1990-10-18     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372434     Medline TA:  Arch Dis Child     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  865-70     Citation Subset:  AIM; IM    
Brompton Hospital, London, Department of Paediatrics.
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MeSH Terms
Exercise / physiology*
Exercise Test
Heart Rate
Oxygen / blood
Oxygen Consumption
Postoperative Complications / physiopathology
Respiration / physiology
Stroke Volume
Superior Vena Cava Syndrome / physiopathology
Transposition of Great Vessels / surgery*
Reg. No./Substance:

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