Document Detail


Exercise-induced cardiac troponin elevation: evidence, mechanisms, and implications.
MedLine Citation:
PMID:  20620736     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Regular physical exercise is recommended for the primary prevention of cardiovascular disease. Although the high prevalence of physical inactivity remains a formidable public health issue, participation in exercise programs and recreational sporting events, such as marathons and triathlons, is on the rise. Although regular exercise training reduces cardiovascular disease risk, recent studies have documented elevations in cardiac troponin (cTn) consistent with cardiac damage after bouts of exercise in apparently healthy individuals. At present, the prevalence, mechanism(s), and clinical significance of exercise-induced cTn release remains incompletely understood. This paper will review the biochemistry, prevalence, potential mechanisms, and management of patients with exercise-induced cTn elevations.
Authors:
Rob Shave; Aaron Baggish; Keith George; Malissa Wood; Jurgen Scharhag; Gregory Whyte; David Gaze; Paul D Thompson
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of the American College of Cardiology     Volume:  56     ISSN:  1558-3597     ISO Abbreviation:  J. Am. Coll. Cardiol.     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-12     Completed Date:  2010-07-30     Revised Date:  2010-12-28    
Medline Journal Info:
Nlm Unique ID:  8301365     Medline TA:  J Am Coll Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  169-76     Citation Subset:  AIM; IM    
Copyright Information:
Copyright (c) 2010 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.
Affiliation:
Brunel University, Uxbridge, Middlesex, United Kingdom. rshave@uwic.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Biological Markers / analysis*
Exercise*
Humans
Myocardium / metabolism
Troponin / analysis*,  metabolism
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Troponin
Comments/Corrections
Comment In:
J Am Coll Cardiol. 2010 Dec 14;56(25):2145; author reply 2145-6   [PMID:  21144979 ]

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