| Exercise-Induced Asthma Symptoms and Nighttime Asthma: Are They Similar to AHR? | |
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MedLine Citation:
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PMID: 20975796 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Background. Asthma experienced during exercise and during the night is based on the presence of airway hyperresponsiveness (AHR). The aim of the present study was to examine whether AHR is a predictor of exercise-induced asthma (EIA) and nighttime symptoms. Material. We included 793 asthmatics subjects with symptoms and a positive asthma test. Results. Mean (SD) FEV1 was 93% (15), 71% had rhinitis, and 62% had atopy. Both EIA and nighttime symptoms were associated with AHR; however, when including other factors of importance in a multivariate analysis, logRDR was eliminated, whereas FEV1% pred (P < .001), smoking (P < .05), atopy (P < .001), sex (P < .001), and treatment (P < .01) were associated with having EIA while dyspnoea (P < .001), cough (P < .001), and eosinophils (P < .01) were associated with frequent night symptoms. The risk of having nighttime awakenings due to asthma was more than twofold higher among those with EIA symptoms than among those without symptoms (OR (CI95%) 2.77 (2.0-3.8) (P < .001)). In Conclusion. EIA and night symptoms are associated with AHR, but other factors of importance eliminated this close association. Night asthma is more closely associated with airway inflammation than AHR. |
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Authors:
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V Backer; L M Rasmussen |
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Publication Detail:
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Type: Journal Article Date: 2009-11-12 |
Journal Detail:
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Title: Journal of allergy Volume: 2009 ISSN: 1687-9791 ISO Abbreviation: J Allergy (Cairo) Publication Date: 2009 |
Date Detail:
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Created Date: 2010-10-26 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101535174 Medline TA: J Allergy (Cairo) Country: United States |
Other Details:
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Languages: eng Pagination: 378245 Citation Subset: - |
Affiliation:
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Department of Respiratory Medicine, Bispebjerg Hospital, University of Copenhagen, 2400 Copenhagen NV, Denmark. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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