| Exercise capacity in an individual with LVAD explantation without heart transplantation. | |
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MedLine Citation:
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PMID: 20436356 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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PURPOSE: Left ventricular assist devices (LVADs) have become a viable treatment alternative to heart transplantation, in some instances providing for a level of improvement of native heart function to allow for device explantation. The aim of this case study was to describe changes in physical work capacity following 9 months of LVAD support. CLINICAL CASE: The patient described here was diagnosed with idiopathic dilated cardiomyopathy and demonstrated worsening heart failure over a 5-year period with a maximum left ventricular end-diastolic diameter of 8.99 cm and an ejection fraction of 15% to 25%. Upon implantation of an LVAD, central hemodynamic function improved and the device was removed after 9 months of support. Left ventricular diastolic and systolic diameter decreased by 39.8% and more than 30%, respectively. The left atrium decreased by 21.7% and ejection fraction was maintained by the LVAD and stabilized at 20%. Four months postexplantation, a cycle ergometry graded cardiopulmonary exercise test was performed. Exercise began at 0 W and increased 25 W per 3-minute stage. RESULTS: The patient showed improvement in peak aerobic capacity when compared to pre-LVAD cardiopulmonary stress tests. Peak oxygen uptake increased from pre-LVAD measures of 11.8 mL x kg(-1) x min(-1) to 17.0 mL x kg(-1) x min(-1). Time to maximal exertion increased from 5 minutes 27 seconds to 15 minutes. CONCLUSION: Results of this case study indicate that significant improvements in native heart function leading to an increased ability to perform work is possible following a period of mechanical unloading through LVAD support. |
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Authors:
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Jeremy A Patterson; Ryan Z Amick; Hussam H Farhoud |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of cardiopulmonary rehabilitation and prevention Volume: 30 ISSN: 1932-751X ISO Abbreviation: J Cardiopulm Rehabil Prev Publication Date: 2010 Jul-Aug |
Date Detail:
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Created Date: 2010-07-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101291247 Medline TA: J Cardiopulm Rehabil Prev Country: United States |
Other Details:
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Languages: eng Pagination: 231-4 Citation Subset: IM |
Affiliation:
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Department of Human Performance Studies, Wichita State University, Wichita, Kansas 67260, USA. jeremy.patterson@wichita.edu |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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