Document Detail

Exercise 201Tl scintigraphy: evaluation of the additional diagnostic value.
MedLine Citation:
PMID:  8429999     Owner:  NLM     Status:  MEDLINE    
The additional diagnostic yield of exercise 201Tl scintigraphy using both visual and quantitative analysis was determined in 221 patients with known or suspected coronary artery disease (CAD). The coronary arteriogram was adopted as the gold standard. After pretest clinical and exercise electrocardiographic data were taken into consideration, scintigraphy added diagnostic accuracy both in the diagnosis of CAD and of multivessel disease. The diagnostic yield of the scintigraphy in terms of sensitivity and specificity was, however, not significant. In 79% (121/153) of the patients, the diagnosis of the presence, or exclusion, of CAD was highly probable (P > 0.80 or P < 0.20) when considering clinical and exercise data. The diagnosis was, however, not significantly improved by the scintigraphic result. Twenty-seven per cent (20/73) returned a negative scintigraphic results with a high (P > 0.80) prescintigraphic probability for CAD and a positive arteriogram. It was concluded that 201Tl scintigraphy has additional diagnostic value after clinical and exercise parameters were taken into consideration in the diagnosis of coronary artery and multiple vessel disease. It is not recommended to refer patients with either a low or high probability of CAD for screening and diagnosis as in a high proportion of patients the diagnosis of CAD could have been made using clinical or exercise data alone.
W P Oosterhuis; M G Niemeyer; A Breeman; A H Zwinderman; C A Ascoop; F J Verzijlbergen; A F Kuijper; E E van der Wall; E K Pauwels
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nuclear medicine communications     Volume:  14     ISSN:  0143-3636     ISO Abbreviation:  Nucl Med Commun     Publication Date:  1993 Feb 
Date Detail:
Created Date:  1993-03-08     Completed Date:  1993-03-08     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8201017     Medline TA:  Nucl Med Commun     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  87-95     Citation Subset:  IM    
Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.
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MeSH Terms
Coronary Disease / diagnosis,  radionuclide imaging*
Evaluation Studies as Topic
Exercise Test
Middle Aged
Sensitivity and Specificity
Thallium Radioisotopes / diagnostic use*
Reg. No./Substance:
0/Thallium Radioisotopes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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