| Executive dysfunction in patients with obstructive sleep apnea syndrome. | |
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MedLine Citation:
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PMID: 19672077 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: To clarify whether patients with obstructive sleep apnea syndrome (OSAS) have executive dysfunction, to identify the domains of executive function affected and to establish the severity of any dysfunction. METHODS: A full-night polysomnography and a comprehensive neuropsychological assessment focusing on executive functions were conducted on 40 newly diagnosed OSAS patients and 20 healthy controls. The severity of dysfunction was analyzed using norm-referenced data. RESULTS: All patients and controls were men. The groups did not differ statistically significantly in terms of age, education or intelligence quotient. Patients showed poorer performance than controls on the copy of the Rey-Osterrieth Complex Figure test, the Block Design, the Trails B of the Trail Making Test and the Intra-Extra Dimensional Set Shifting test. Based on the normative data, most OSAS patients performed at a normal level, but a few patients had either mild dysfunction (2.5-12.5%) or moderate to severe dysfunction (5-15%). CONCLUSIONS: OSAS patients have lower set-shifting and analysis/synthesis performance than healthy controls. According to the normative data, most patients in the present study had normal performance, but there were also a few patients with more serious deficits. |
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Authors:
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Tiia Saunamäki; Sari-Leena Himanen; Olli Polo; Mervi Jehkonen |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-08-06 |
Journal Detail:
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Title: European neurology Volume: 62 ISSN: 1421-9913 ISO Abbreviation: Eur. Neurol. Publication Date: 2009 |
Date Detail:
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Created Date: 2009-09-04 Completed Date: 2009-11-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0150760 Medline TA: Eur Neurol Country: Switzerland |
Other Details:
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Languages: eng Pagination: 237-42 Citation Subset: IM |
Copyright Information:
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2009 S. Karger AG, Basel |
Affiliation:
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Department of Neurology and Rehabilitation, Tampere University Hospital, Tampere, Finland. tiia.saunamaki@uta.fi |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Cognition Disorders / complications, physiopathology* Humans Intelligence Tests Interviews as Topic Male Middle Aged Neuropsychological Tests Patient Selection Polysomnography Severity of Illness Index Sleep Apnea, Obstructive / complications, physiopathology* Statistics, Nonparametric |
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