Document Detail


Executive Function and Type 2 Diabetes: Putting the Pieces Together.
MedLine Citation:
PMID:  22135708     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The devastating impact of type 2 diabetes mellitus (DM) on vascular, renal, retinal, and peripheral nerve function has been well documented. However, there is also evidence that older adults with this disease exhibit impairments in the planning, coordinating, sequencing, and monitoring of cognitive operations, collectively known as executive function. Although poorly understood, it is possible that disturbances in executive function, particularly within the dimension of time sharing, contribute to the gait abnormalities and increased risk for falls, functional impairments, and disabilities associated with type 2 DM. Despite this, the relationships between executive function and functional abilities remain poorly understood in this population. Current neuropsychological research regarding the concept of executive function is presented as a framework upon which to examine the integrity of this critical cognitive entity in adults with type 2 DM. Additionally, the pathophysiological mechanisms thought to underlie diabetes-related executive dysfunction are explored, and the possible contributions of executive deficits to the impairments in gait and function observed in the older population with type 2 DM summarized. The article concludes with a brief discussion of dual-task assessment and intervention strategies which may facilitate the care and rehabilitation of this growing patient population.
Authors:
Jason Rucker; Joan M McDowd; Patricia M Kluding
Related Documents :
21263438 - Cognitive function, dementia and type 2 diabetes mellitus in the elderly.
7851068 - Serum lipoprotein levels and plasma concentrations of insulin, intact and 32, 33 split ...
10808058 - Insulin antibody response to bovine insulin therapy: functional significance among insu...
10073958 - Relative contribution of insulin and its precursors to fibrinogen and pai-1 in a large ...
2500578 - Sorbinil suppresses glomerular prostaglandin production in the streptozotocin diabetic ...
15016818 - Protein phosphatase-2c alpha as a positive regulator of insulin sensitivity through dir...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-1
Journal Detail:
Title:  Physical therapy     Volume:  -     ISSN:  1538-6724     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0022623     Medline TA:  Phys Ther     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
J. Rucker, PT, MSPT, Department of Physical Therapy and Rehabilitation Science, University of Kansas Medical Center, 3901 Rainbow Blvd, MS 2002, Kansas City, KS 66160 (USA).
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Defining, Agreeing on, and Testing an International Physical Therapy Core Data Set: Results of a Fea...
Next Document:  Understanding Falls in Multiple Sclerosis: Association of Mobility Status, Concerns About Falling, a...