Document Detail


Excretion of guanidino-derivates in urine of hyperargininemic patients.
MedLine Citation:
PMID:  819629     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Quantitative determinations were made for seven guanidino-derivates in urine of patients affected with hyperargininemia, lysine cystinuria, healthy children and adults, goats and monkey. The amount of all seven guanidino-derivates excreted in the urine with the exception of guanidino-succinic acid was large in the case of hyperargininemic patients. Guanidino-succinic acid is found in traces in the urine of these patients, even after arginine loading tests. There is apparently no similarity concerning the guanidino-derivates between the patients with hyperargininemia, a pathological status, and the arginase deficiency in goats and monkeys, a physiological phenomenon.
Authors:
P Wiechert; J Mortelmans; F Lavinha; R Clara; H G Terheggen; A Lowenthal
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal de génétique humaine     Volume:  24     ISSN:  0021-7743     ISO Abbreviation:  J Genet Hum     Publication Date:  1976 Mar 
Date Detail:
Created Date:  1976-08-23     Completed Date:  1976-08-23     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  2983308R     Medline TA:  J Genet Hum     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  61-72     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Animals
Arginine / blood,  metabolism*
Child
Female
Goats
Guanidines / urine*
Haplorhini
Humans
Hyperargininemia*
Male
Metabolism, Inborn Errors / genetics*
Species Specificity
Chemical
Reg. No./Substance:
0/Guanidines; 74-79-3/Arginine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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