| Excretion of cytomegalovirus in mothers: observations after delivery of congenitally infected and normal infants. | |
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MedLine Citation:
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PMID: 6282987 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Shedding of cytomegalovirus (CMV) was studied in 142 women who gave birth to congenitally infected infants and in 81 seropositive control mothers (mothers of uninfected infants). Viral cultures from the throat, vagina, and urine were obtained at intervals between one month and nearly 12 years after delivery. In both groups the prevalence of excretion of CMV was greater in younger women and fell to low levels by age 30. Considering all of the sites of infection, 60% of the mothers of infected infants were shedding CMV within the first three months post partum compared with 18% of the control mothers; CMV shedding rates declined during the first 12 months post partum to 35% in the former group and to 3% in the latter. More than three years after delivery, seven (15%) of 45 mothers who transmitted CMV still had viruria. The excretion of CMV is common and persistent in mothers of children with congenital infections due to CMV. |
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Authors:
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R F Pass; S Stagno; M E Dworsky; R J Smith; C A Alford |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The Journal of infectious diseases Volume: 146 ISSN: 0022-1899 ISO Abbreviation: J. Infect. Dis. Publication Date: 1982 Jul |
Date Detail:
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Created Date: 1982-08-26 Completed Date: 1982-08-26 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0413675 Medline TA: J Infect Dis Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1-6 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Age Factors Cytomegalovirus / isolation & purification* Cytomegalovirus Infections / congenital, microbiology*, transmission, urine Female Humans Infant, Newborn Pharynx / microbiology Pregnancy Pregnancy Complications, Infectious* / microbiology Socioeconomic Factors Vagina / microbiology |
| Grant Support | |
ID/Acronym/Agency:
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5-MO1-RR32/RR/NCRR NIH HHS; HD-106999/HD/NICHD NIH HHS; T32-A107041//PHS HHS |
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