Document Detail

Excision of juvenile pilocytic astrocytoma of the midbrain after radiotherapy.
MedLine Citation:
PMID:  16902345     Owner:  NLM     Status:  MEDLINE    
A 13-year-old girl presented with consciousness disturbance, right hemiparesis, and impairment of hearing, swallowing, and ocular movements. A magnetic resonance image demonstrated marked hydrocephalus due to a large cystic tumor (40 x 40 x 30 mm) in the midbrain. Emergency ventricular drainage and stereotactic cyst puncture dramatically improved her condition. Since her family did not agree to surgery on the brain stem, radiotherapy was performed after ventriculoperitoneal shunting. Conventional radiotherapy of 50.4 Gy was temporarily effective, and the growth of the tumor was stabilized until approximately 8 months later when regrowth was noticed. At this stage, with the consent of her family, the tumor was removed via an infratentorial supracerebellar approach. The pathological diagnosis was juvenile pilocytic astrocytoma. The postoperative course was uneventful. No recurrence has been observed during the follow-up period of more than 6 years. This case study shows that initial excision may be appropriate for some low-grade focal lesions in the midbrain when the histological diagnosis and consent have been obtained.
Koji Tsuboi; Wakoto Matsuda; Kazuhiro Nakamura; Shingo Takano; Akira Matsumura
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric neurosurgery     Volume:  42     ISSN:  1016-2291     ISO Abbreviation:  Pediatr Neurosurg     Publication Date:  2006  
Date Detail:
Created Date:  2006-08-11     Completed Date:  2006-10-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9114967     Medline TA:  Pediatr Neurosurg     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  311-5     Citation Subset:  IM    
Copyright Information:
Copyright 2006 S. Karger AG, Basel.
Department of Neurosurgery, Doctoral Program in Functional and Regulatory Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan.
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MeSH Terms
Astrocytoma / radiotherapy,  surgery*
Brain Stem Neoplasms / radiotherapy,  surgery*
Follow-Up Studies
Neoplasm Recurrence, Local / surgery*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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