Document Detail


Excimer laser for various degrees of myopia. A new model estimating the immediate response, the regression, the final response and the time relationship.
MedLine Citation:
PMID:  9591939     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To demonstrate a unified model for various degrees of myopia, characterizing the response-time relationship and its influence of topical corticosteroids. METHODS: 84 eyes were treated with excimer laser for myopia (median -7.1 D). 50 eyes received topical NSAID for 4 days (group 1), and 34 eyes (group 2) were further treated postoperatively with bandage lens and topical corticosteroids for three months. The response-time relationship was expressed as P(t)=a+b*exp(k*t), where P(t) is the response expressed as the percent change in dioptric power to the postoperative time t, a is the final percent response, b is the total percent regression and k the time constant. a+b express the percent immediate response and T1/2=0.69/k denote the time within which half of the total regression has occurred. RESULTS: The immediate and final responses were significantly larger in group 2 (128.9% and 70.5%) compared with group 1 (110.5% and 59.8%). T1/2 was significantly longer in group 2 (2.1 month) compared with group 1 (0.8 month) CONCLUSION: Use of bandage lens together with steroids significantly influences the response-time relationship after excimer laser treatment for myopia.
Authors:
C Edmund
Related Documents :
9100119 - Exfoliation syndrome and phacoemulsification.
11709249 - Phacoemulsification of brunescent and black cataracts.
17189799 - Comparison of pseudophakic dysphotopsia with akreos adapt and sn60-at intraocular lenses.
7831029 - Long-term follow-up of patients with familial subepithelial amyloidosis of the cornea.
24116959 - Transition to ustekinumab in patients with moderate-to-severe psoriasis and inadequate ...
18850549 - Stability of silicone band frontalis suspension for the treatment of severe unilateral ...
22829329 - Tka outcomes after prior bone and soft tissue knee surgery.
19395059 - Nasal leech infestation in children: comparison of two different innovative techniques.
24876569 - Dialbetics: a novel smartphone-based self-management support system for type 2 diabetes...
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Acta ophthalmologica Scandinavica     Volume:  76     ISSN:  1395-3907     ISO Abbreviation:  Acta Ophthalmol Scand     Publication Date:  1998 Apr 
Date Detail:
Created Date:  1998-06-19     Completed Date:  1998-06-19     Revised Date:  2008-03-17    
Medline Journal Info:
Nlm Unique ID:  9507578     Medline TA:  Acta Ophthalmol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  131-7     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, Rigshospitalet, University of Copenhagen, Denmark.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Administration, Topical
Adrenal Cortex Hormones / therapeutic use
Adult
Anti-Inflammatory Agents, Non-Steroidal / administration & dosage,  therapeutic use
Cornea / physiopathology
Humans
Laser Therapy*
Middle Aged
Myopia / drug therapy,  physiopathology,  surgery*
Occlusive Dressings
Postoperative Period
Refraction, Ocular / physiology
Time Factors
Treatment Outcome
Visual Acuity / physiology
Chemical
Reg. No./Substance:
0/Adrenal Cortex Hormones; 0/Anti-Inflammatory Agents, Non-Steroidal

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Pharmacokinetic studies of mitoxantrone and one of its metabolites in serum and urine in patients wi...
Next Document:  Paired arcuate keratotomy for congenital and post-keratoplasty astigmatism.