Document Detail


Exchange transfusion in severe hyperbilirubinemia: an experience in northwest Iran.
MedLine Citation:
PMID:  21043381     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Our goal was to determine the indications for exchange transfusion (ECT) and the rates of ECT-related adverse events in neonatal hyperbilirubinemia. We reviewed retrospectively the medical charts of all newborns that had undergone ECT over three years from January 2006 to December 2008. Causes of jaundice, demographic data of the patients, and details of ECT and ECT-related adverse events were recorded. A total of 176 ECT procedures were performed in 150 neonates in the three-year study period. The mean total serum bilirubin before ECT was 29.59 +/- 6.88 mg/dl. Those infants requiring more than one ECT had higher total serum bilirubin than neonates with single ECT, but the difference was not significant (35.66 +/- 12.21 vs. 29.12 +/- 6.30 mg/dl, p = 0.09). The most common cause of ECT was ABO incompatibility (49.3%), Rh disease (7.3%) and idiopathic (28%). Among the adverse events related to ECT, thrombocytopenia (36.4%), hypocalcemia (25.5%), apnea (20%), and infection (10.9%) were noted commonly. No case of ECT-related mortality was observed. All of the adverse events resolved completely before discharge. ABO isoimmunization was the most common cause of ECT in this study. The majority of adverse events associated with ECT are asymptomatic and reversible.
Authors:
Seddigheh Hosseinpour Sakha; Manizheh Mostafa Gharehbaghi
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Turkish journal of pediatrics     Volume:  52     ISSN:  0041-4301     ISO Abbreviation:  Turk. J. Pediatr.     Publication Date:    2010 Jul-Aug
Date Detail:
Created Date:  2010-11-03     Completed Date:  2010-12-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0417505     Medline TA:  Turk J Pediatr     Country:  Turkey    
Other Details:
Languages:  eng     Pagination:  367-71     Citation Subset:  IM    
Affiliation:
Tabriz University, Medical Science, Tabriz, Iran.
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MeSH Terms
Descriptor/Qualifier:
Chi-Square Distribution
Exchange Transfusion, Whole Blood / adverse effects*
Female
Humans
Hyperbilirubinemia, Neonatal / therapy*
Infant, Newborn
Iran
Male
Retrospective Studies

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