Document Detail

Excessive iodine intake and ultrasonographic thyroid abnormalities in schoolchildren.
MedLine Citation:
PMID:  19554806     Owner:  NLM     Status:  MEDLINE    
High nutritional levels of iodine may induce a higher prevalence of autoimmune thyroiditis, hypothyroidism, goiter, as well as hyperthyroidism, mostly in the elderly. This study assessed thyroid volume and ultrasonographic abnormalities as well as urinary iodine excretion (UIE) in 964 schoolchildren living in an iodine-sufficient area in southern Brazil. Thyroid volume correlated with age and body surface area in boys and girls. In 76.8% of the children, UIE was above 300 microg/l, with higher levels among boys compared to girls (484.2 microg/l vs 435.3 microg/l, p < 0.001). Thyroid abnormalities detected by ultrasonography included hemiagenesis (0.5%), nodules (0.2%), cysts (0.7%), and hypoechogenicity (11.7%). Goiter was present in 1.9% of the children. Hypoechogenicity, a relevant marker of autoimmune thyroiditis, was the most common abnormality found in our study, and this may be linked to excessive iodine intake.
Glaucia C Duarte; Eduardo K Tomimori; Rosalinda Y A de Camargo; Regina M Catarino; Jerenice E Ferreira; Meyer Knobel; Geraldo Medeiros-Neto
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pediatric endocrinology & metabolism : JPEM     Volume:  22     ISSN:  0334-018X     ISO Abbreviation:  J. Pediatr. Endocrinol. Metab.     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-06-26     Completed Date:  2009-07-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9508900     Medline TA:  J Pediatr Endocrinol Metab     Country:  England    
Other Details:
Languages:  eng     Pagination:  327-34     Citation Subset:  IM    
Thyroid Unit, Division of Endocrinology, Department of Clinical Medicine, University of São Paulo Medical School, Brazil.
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MeSH Terms
Body Surface Area
Brazil / epidemiology
Iodine / administration & dosage,  adverse effects*,  urine
Thyroid Diseases / epidemiology,  ultrasonography*
Thyroid Gland / drug effects,  ultrasonography*
Reg. No./Substance:

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