Document Detail


The exceptional ethics of the investigator-subject relationship.
MedLine Citation:
PMID:  20026526     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This article concerns the validity of six canonical rules that institutional review boards use to constrain the behavior of investigators. These rules require investigators to design their studies in a scientifically valid way, not pay their subjects to take risks, minimize risks to their subjects, secure for their subjects access to effective interventions post-trial, not pay their subjects too much and allow their subjects to withdraw from the study unconditionally. Enforcement of these rules is problematic because there are other relationships that seem to be like the investigator-subject relationship in all ethically relevant respects, such as the employer-employee and volunteer organizer-volunteer relationships, to which we would not dream of applying these same rules. Applying these rules in one context but not the others is a violation of ethical consistency I label "exceptionalism." We should conclude that it is time to reexamine the validity of the six rules.
Authors:
Benjamin Sachs
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-12-21
Journal Detail:
Title:  The Journal of medicine and philosophy     Volume:  35     ISSN:  1744-5019     ISO Abbreviation:  J Med Philos     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-01-14     Completed Date:  2010-03-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7610512     Medline TA:  J Med Philos     Country:  United States    
Other Details:
Languages:  eng     Pagination:  64-80     Citation Subset:  E; IM    
Affiliation:
Program in Environmental Studies and Center for Bioethics, New York University, 285 Mercer Street 9th Floor, New York, NY 10012, USA. sachs@nyu.edu
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MeSH Terms
Descriptor/Qualifier:
Biomedical Research / ethics*
Ethical Analysis
Humans
Patient Dropouts
Philosophy, Medical
Professional-Patient Relations*
Research Design
Research Personnel / ethics*
Research Subjects*
Risk Reduction Behavior

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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