| Exceptional bone metastasis of basal cell carcinoma in Gorlin-Goltz syndrome. | |
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MedLine Citation:
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PMID: 19996568 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Basal cell carcinoma (BCC), the most prevalent form of cancer worldwide, is a malignant skin neoplasm. It is locally invasive, with an exceptional incidence of reported metastasis. It can also be part of the Gorlin-Goltz syndrome, an autosomal dominant genetic disorder with high penetrance and variable expressivity, which is principally characterized by cutaneous BCC, odontogenic keratocysts, palmar and/or plantar pits, and falx cerebri calcification. OBSERVATION: We report the exceptional clinical observation of a 54-year-old man presenting bone metastasis from BCC in Gorlin-Goltz syndrome. CONCLUSION: Less than 300 cases of metastatic BCC have been reported in the literature. The present case is the second associated with Gorlin-Goltz syndrome. |
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Authors:
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Tatiana Lamon; Stephane Gerard; Nicolas Meyer; Benjamin Losfeld; Gabor Abellan van Kan; Laurent Balardy; Bruno Vellas |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2009-12-04 |
Journal Detail:
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Title: Dermatology (Basel, Switzerland) Volume: 220 ISSN: 1421-9832 ISO Abbreviation: Dermatology (Basel) Publication Date: 2010 |
Date Detail:
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Created Date: 2010-01-21 Completed Date: 2010-04-12 Revised Date: 2010-04-22 |
Medline Journal Info:
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Nlm Unique ID: 9203244 Medline TA: Dermatology Country: Switzerland |
Other Details:
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Languages: eng Pagination: 57-9 Citation Subset: IM |
Copyright Information:
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Copyright 2009 S. Karger AG, Basel. |
Affiliation:
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G?rontop?le, Department of Geriatric Medicine, CHU Toulouse, Toulouse, France. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Bone Neoplasms
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radiography,
secondary* Carcinoma, Basal Cell / radiography, secondary* European Continental Ancestry Group Focal Dermal Hypoplasia / genetics, pathology* Humans Male Middle Aged Neoplasm Metastasis Pain / etiology Receptors, Cell Surface / genetics Skin Neoplasms / pathology* |
| Chemical | |
Reg. No./Substance:
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0/Receptors, Cell Surface; 0/patched receptors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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