| Excellent survival and low incidence of arrhythmias, stroke and heart failure long-term after surgical ASD closure at young age. A prospective follow-up study of 21-33 years. | |
| | |
MedLine Citation:
|
PMID: 12573276 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
AIMS: Although studies have suggested good long-term results, arrhythmias, pulmonary hypertension and left ventricular dysfunction are mentioned as sequelae long-term after surgical atrial septal defect closure at young age. Most studies were performed only by questionnaire and in a retrospective manner. The long-term outcome is very important with regard to future employment and acceptance on insurance schemes. METHODS AND RESULTS: One hundred and thirty-five consecutive ASD-patients, operated on in childhood, were studied longitudinally with ECG, echocardiography, exercise testing and Holter-recording 15 (10-22) and 26 (21-33) years after surgery. During follow-up no cardiovascular mortality, stroke, heart failure and no pulmonary hypertension occurred. Symptomatic supraventricular tachyarrhythmias were present in 6% after 15 years, and an additional 2% occurred in the last decade; 5% needed pacemaker implantation. No relation was found between arrhythmias and type of ASD, baseline data, right ventricular dimensions, or age at operation. Left and right ventricular function and dimension remained unchanged. Slightly more patients had right atrial dilatation at last follow-up. Exercise capacity was comparable with the normal Dutch population. CONCLUSIONS: The long-term outcome after ASD closure at young age shows excellent survival and low morbidity. The incidence of supraventricular arrhythmias is lower than in natural history studies of ASD patients and also lower than after surgical correction at adult age. |
| | |
Authors:
|
J W Roos-Hesselink; F J Meijboom; S E C Spitaels; R van Domburg; E H M van Rijen; E M W J Utens; A J J C Bogers; M L Simoons |
Related Documents
:
|
19346016 - The use of impella recover in the treatment of post-infarction ventricular septal defec... 16580436 - Neurodevelopmental outcome after early repair of a ventricular septal defect with or wi... 8457116 - Management of airway obstruction in patients with congenital heart defects. 15227026 - Echocardiographic evaluation of left ventricular function, mass and wall stress in chil... 16580416 - Right ventricular enlargement mimicking electrocardiographic left ventricular pacing. 7014026 - Coronary-prone behavior and coronary heart disease: a critical review. the review panel... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: European heart journal Volume: 24 ISSN: 0195-668X ISO Abbreviation: Eur. Heart J. Publication Date: 2003 Jan |
Date Detail:
|
Created Date: 2003-02-07 Completed Date: 2003-03-19 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8006263 Medline TA: Eur Heart J Country: England |
Other Details:
|
Languages: eng Pagination: 190-7 Citation Subset: IM |
Affiliation:
|
Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Age Factors Arrhythmias, Cardiac / etiology, mortality Cardiac Output, Low / etiology, mortality Child Child, Preschool Female Heart Function Tests Heart Septal Defects, Atrial / mortality, surgery* Humans Incidence Infant Infant, Newborn Longitudinal Studies Male Medical History Taking Netherlands / epidemiology Physical Examination Postoperative Complications / etiology, mortality Stroke / etiology, mortality Survival Analysis Survival Rate |
| Comments/Corrections | |
Comment In:
|
Eur Heart J. 2003 Oct;24(19):1797; author reply 1797-8
[PMID:
14522578
]
Eur Heart J. 2003 Jan;24(2):130-2 [PMID: 12573268 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Time-based risk assessment after myocardial infarction. Implications for timing of discharge and app...
Next Document: Lipoprotein(a), Chlamydia pneumoniae, leptin and tissue plasminogen activator as risk markers for va...