| Exanthema after a stress Tc-99m sestamibi study: continue with a rest sestamibi study? | |
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MedLine Citation:
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PMID: 21470366 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Purpose: A mild allergic reaction assumed to be caused by injection of Tc-99m sestamibi for a stress myocardial perfusion imaging (MPI) is presented. We want to discuss the risk involved in completing the MPI with another sestamibi injection, and the precautions and possible treatment in case of a further reaction. Material and methods: A patient experienced a maculo-papular exanthema, i.e. a mild, probably allergic, adverse event (AE) after a stress MPI including administration of a dose of Tc-99m sestamibi. A rest MPI was needed to decide whether coronary bypass surgery should be performed. After prophylactic treatment with antihistamine and corticosteroid, an uneventful rest MPI was performed. Discussion and conclusion: International recommendations or guidelines related to treatment of AEs after nuclear medicine studies do not exist. Serious AEs in nuclear medicine are very rare, but anaphylactic reactions have been reported and may be life threatening. If repeated administration of the radio-pharmaceutical must be given, the prophylactic and therapeutic interventions should follow general international guidelines for allergic reactions. |
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Authors:
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Birger Hesse; Niels Vinberg; Holger Mosbech |
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Publication Detail:
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Type: Journal Article Date: 2011-01-23 |
Journal Detail:
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Title: Clinical physiology and functional imaging Volume: 31 ISSN: 1475-097X ISO Abbreviation: Clin Physiol Funct Imaging Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-04-07 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101137604 Medline TA: Clin Physiol Funct Imaging Country: England |
Other Details:
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Languages: eng Pagination: 246-8 Citation Subset: IM |
Copyright Information:
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© 2011 The Authors. Clinical Physiology and Functional Imaging © 2011 Scandinavian Society of Clinical Physiology and Nuclear Medicine. |
Affiliation:
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Clinic of Clinical Physiology and Nuclear Medicine & PET, Rigshospitalet, University of Copenhagen, Copenhagen The Isotope Agency, Capital Region Pharmacy, Herlev Department of Allergology, Rigshospitalet and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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