Document Detail


Examining the positive effects of exercise in intubated adults in ICU: a prospective repeated measures clinical study.
MedLine Citation:
PMID:  22458998     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Determining the optimal timing and progression of mobility exercise has the potential to affect functional recovery of critically ill adults. This study compared standard care with care delivered using a mobility protocol. We examined the effects of exercise on vital signs and inflammatory biomarkers and the effects of the nurse-initiated mobility protocol on outcomes.
METHODS: Prospective, repeated measures study with a control (standard care) and intervention (protocol) period.
RESULTS: 75 heterogeneous subjects admitted to a Medical or Surgical intensive care unit (ICU) were enrolled. In <5% of exercise periods, there was a concerning alteration in respiratory rate or peripheral oxygen saturation; no other adverse events occurred. Findings suggested the use of a protocol with one 20 minute episode of exercise daily for 2 or more days reduced ICU length of stay. Duration of exercise was linked to increased IL-10, suggesting brief episodes of low intensity exercise positively altered inflammatory dysregulation in this sample.
CONCLUSION: A growing body of evidence demonstrates that early, progressive exercise has significant benefits to intubated adults. These results should encourage clinicians to add mobility protocols to the care of ICU adults and lead to future studies to determine optimal "dosing" of exercise in ICU patients.
Authors:
Chris Winkelman; Kimberly D Johnson; Rana Hejal; Nahida H Gordon; James Rowbottom; Janis Daly; Karen Peereboom; Alan D Levine
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2012-03-28
Journal Detail:
Title:  Intensive & critical care nursing : the official journal of the British Association of Critical Care Nurses     Volume:  28     ISSN:  1532-4036     ISO Abbreviation:  Intensive Crit Care Nurs     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-13     Completed Date:  2013-11-22     Revised Date:  2013-12-06    
Medline Journal Info:
Nlm Unique ID:  9211274     Medline TA:  Intensive Crit Care Nurs     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  307-18     Citation Subset:  N    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
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MeSH Terms
Descriptor/Qualifier:
Aged
Biological Markers / blood
Clinical Protocols
Critical Care* / methods
Exercise* / psychology
Female
Humans
Inflammation Mediators / blood
Intensive Care
Intensive Care Units
Male
Muscle Strength / physiology
Prospective Studies
Recovery of Function
Respiration, Artificial
Grant Support
ID/Acronym/Agency:
M01 RR000080/RR/NCRR NIH HHS; M01 RR00080/RR/NCRR NIH HHS; UL1 RR024989/RR/NCRR NIH HHS; UL1 RR24989/RR/NCRR NIH HHS; UL1 TR000439/TR/NCATS NIH HHS
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Inflammation Mediators
Comments/Corrections
Comment In:
Intensive Crit Care Nurs. 2012 Dec;28(6):318-9; author reply 319-20   [PMID:  22832382 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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