Document Detail

Examination of fragment dose contribution in heavy ion radiotherapy.
MedLine Citation:
PMID:  11944059     Owner:  NLM     Status:  MEDLINE    
Heavy-ion radiotherapy is an efficient method for the treatment of deep-seated tumors, because the stopping of ions in a tissue delivers the maximal absorbed dose to the tumor-affected areas with minimal damage to the healthy tissues. However, heavy ions can undergo nuclear reactions, giving products with lower Z-values and hence a longer range in the tissue. This causes a dose increase beyond the mean range of the primary beam. The contribution of such reaction products was examined in an experiment where a stack of tissue-like targets interleaved with CR-39 etched track detectors (ETD) was irradiated with heavy ions. The analysis was performed using a recently developed technique of trajectory tracing, which enables the spectroscopy of fragments with different Z-values.
Marko Giacomelli; Radomir Ilic; Jure Skvarc
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cellular & molecular biology letters     Volume:  7     ISSN:  1425-8153     ISO Abbreviation:  Cell. Mol. Biol. Lett.     Publication Date:  2002  
Date Detail:
Created Date:  2002-04-10     Completed Date:  2002-07-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9607427     Medline TA:  Cell Mol Biol Lett     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  112-4     Citation Subset:  IM    
Jozef Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia.
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MeSH Terms
Carbon Isotopes
Heavy Ions / therapeutic use*
Paraffin / radiation effects
Radiotherapy / methods*
Relative Biological Effectiveness
Reg. No./Substance:
0/Carbon Isotopes; 8002-74-2/Paraffin

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