Document Detail


Examination of faecal Bifidobacterium populations in breast- and formula-fed infants during the first 18 months of life.
MedLine Citation:
PMID:  20864478     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Bifidobacteria in the infant faecal microbiota have been the focus of much interest, especially during the exclusive milk-feeding period and in relation to the fortification of infant formulae to better mimic breast milk. However, longitudinal studies examining the diversity and dynamics of the Bifidobacterium population of infants are lacking, particularly in relation to the effects of weaning. Using a polyphasic strategy, the Bifidobacterium populations of breast- and formula-fed infants were examined during the first 18 months of life. Bifidobacterium-specific denaturing gradient gel electrophoresis demonstrated that breast-fed infants harboured greater diversity than formula-fed infants and the diversity of the infants' Bifidobacterium populations increased with weaning. Twenty-seven distinctive banding profiles were observed from ∼1100 infant isolates using ribosomal intergenic spacer analysis, 14 biotypes of which were confirmed to be members of the genus Bifidobacterium. Two profiles (H, Bifidobacterium longum subsp. infantis; and I, Bifidobacterium bifidum) were common culturable biotypes, seen in 9/10 infants, while profile E (Bifidobacterium breve) was common among breast-fed infants. Overall, inter- and intra-individual differences were observed in the Bifidobacterium populations of infants between 1 and 18 months of age, although weaning was associated with increased diversity of the infant Bifidobacterium populations. Breast-fed infants generally harboured a more complex Bifidobacterium microbiota than formula-fed infants.
Authors:
Laure C Roger; Adele Costabile; Diane T Holland; Lesley Hoyles; Anne L McCartney
Related Documents :
3572318 - Selection of infant feeding method: a population-based study in a rural area.
19809008 - Use of duloxetine in pregnancy and lactation.
3894468 - Successful breast feeding: the mother's dilemma.
19825208 - Determinants of breast-feeding in a finnish birth cohort.
3738918 - Urine neuron-specific enolase and its clinical implication in patients with neuroblastoma.
11466248 - Reduced incidence of retinopathy of prematurity.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-09-23
Journal Detail:
Title:  Microbiology (Reading, England)     Volume:  156     ISSN:  1465-2080     ISO Abbreviation:  Microbiology (Reading, Engl.)     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9430468     Medline TA:  Microbiology     Country:  England    
Other Details:
Languages:  eng     Pagination:  3329-41     Citation Subset:  IM    
Affiliation:
Microbial Ecology and Health Group, Food Microbial Sciences Unit, Department of Food and Nutritional Sciences, University of Reading, Whiteknights Campus, PO Box 226, Reading RG6 6AP, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Regulation of the nitrate reductase operon narKGHJI by the cAMP-dependent regulator GlxR in Coryneba...
Next Document:  Conservation, rearrangement, and deletion of gene pairs during the evolution of four grass genomes.