| Examination of the early conceptus. | |
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MedLine Citation:
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PMID: 2064529 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The pathologist encounters the early, first-trimester conceptus as a product of spontaneous or surgical abortion or as a specimen from ectopic, usually tubal, gestation. In the vast majority of cases of spontaneous abortion, the embryo/fetus has been dead for 1 week to several weeks and is most often lost in the process of uterine emptying; the placenta, accordingly, stands as the main "witness" of the abortive process. The fact of embryonic/fetal death is established and dated through an interpretation of gross and microscopic changes in the villous stroma, including its vessels and the embryonic erythrocytes therein. Elective abortions performed for social reasons occasionally yield abnormal findings that suggest gestations otherwise destined to eventual spontaneous abortion. Other therapeutic abortions are indicated by abnormal sonographic or cytogenetic findings that may be correlated with the morphologic features of the evacuated conceptus. Cytogenetic abnormalities correlate to a high degree with embryonic growth disorganization and with early death, usually before the fetal stage (30 mm) is reached. Adequate sampling of the placenta, its membranes, and of the embryo/fetus is recommended. For cytogenetic studies, clean, viable specimens must be obtained; these are most often required in cases of habitual abortion. |
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Authors:
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A E Szulman |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Archives of pathology & laboratory medicine Volume: 115 ISSN: 0003-9985 ISO Abbreviation: Arch. Pathol. Lab. Med. Publication Date: 1991 Jul |
Date Detail:
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Created Date: 1991-08-06 Completed Date: 1991-08-06 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7607091 Medline TA: Arch Pathol Lab Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 696-700 Citation Subset: AIM; IM |
Affiliation:
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Department of Pathology, Magee-Womens Hospital, Pittsburgh, PA 15213. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Spontaneous
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pathology* Embryo, Mammalian / pathology* Female Fetal Death / etiology, pathology Humans Placenta / pathology Pregnancy Pregnancy Trimester, First Specimen Handling |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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