Document Detail

Examination of cardiovascular and peripheral autonomic function in the ICU: a pilot study.
MedLine Citation:
PMID:  23275003     Owner:  NLM     Status:  MEDLINE    
EXCLUSION CRITERIA: polyneuropathy, autonomic neuropathy, admission after stroke, spinal cord injury or cardiac arrest. For the CFT, a cold pack was applied to the forehead to measure the maximal increase in RR interval. The simulated SWT was used and wrinkling was assessed on a five-point scale. HRV was investigated using power spectral analysis of continuous 5-min ECG recordings. Twelve critically ill patients were included (mean age 54). No adverse effects for the CFT and SWT were noted. The CFT could be performed in 10 patients and showed an abnormal response in 9. The SWT could be performed in 11 patients; results were abnormal in 6. HRV analysis showed decreased HRV in all patients. CFT and HRV responses were correlated with each other, no correlation was found between SWT and CFT or HRV results. The CFT and SWT are feasible and safe in critically ill patients. Cardiovascular dysfunction may be more prevalent in critical illness than peripheral sympathetic dysfunction. Influence of confounders and further validation of these tests needs to be investigated.
L Wieske; E R Kiszer; M J Schultz; C Verhamme; I N van Schaik; J Horn
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2012-12-30
Journal Detail:
Title:  Journal of neurology     Volume:  260     ISSN:  1432-1459     ISO Abbreviation:  J. Neurol.     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2013-06-07     Completed Date:  2014-01-15     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  0423161     Medline TA:  J Neurol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1511-7     Citation Subset:  IM    
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MeSH Terms
Autonomic Nervous System / physiopathology
Cardiovascular System / physiopathology
Cohort Studies
Critical Illness*
Diagnostic Techniques, Cardiovascular*
Diagnostic Techniques, Neurological*
Heart Rate / physiology
Intensive Care Units*
Middle Aged
Pilot Projects
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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