Document Detail


Examination of blood levels of mercurials in practicing dentists using cold-vapor atomic absorption spectrometry.
MedLine Citation:
PMID:  3626527     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The toxicity of mercury compounds in dentistry has been an issue of increasing concern. Relatively few data are available concerning the possible in vivo biotransformation of elemental mercury from dental amalgam into more toxic organic mercurials. The present study was designed to evaluate the existence of this in vivo pathway in dentists who work in a confined environment where metallic mercury vapor is constantly present. Two hundred five practicing dentists and 24 nondental controls were asked to participate in this study. The total, inorganic, and organic mercury contents of blood were determined by syringe-injection cold-vapor atomic absorption spectrometry. The student t-test indicates that the total and inorganic mercury levels in blood are significantly different between dentists and nondental controls at the significant level of p less than or equal to 0.05. The organomercurial levels are, however, insignificant at the same test level. This implies that high total and inorganic mercury levels are not correlated with high organomercurial levels in the blood of practicing dentists. Therefore, significant enzymatic conversion of inorganic to organic mercury compounds does not occur in vivo.
Authors:
S B Chang; C Siew; S E Gruninger
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of analytical toxicology     Volume:  11     ISSN:  0146-4760     ISO Abbreviation:  J Anal Toxicol     Publication Date:    1987 Jul-Aug
Date Detail:
Created Date:  1987-09-29     Completed Date:  1987-09-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7705085     Medline TA:  J Anal Toxicol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  149-53     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Dentists*
Humans
Mercury / blood*
Methylmercury Compounds / blood
Spectrophotometry, Atomic
Chemical
Reg. No./Substance:
0/Methylmercury Compounds; 7439-97-6/Mercury

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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