| An Examination of Psychotropic Medication Side Effects: does taking a greater number of psychotropic medications from different classes affect presentation of side effects in adults with ID? | |
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MedLine Citation:
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PMID: 20542660 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study examined whether the number of psychotropic medications an individual is taking across classes influences side effects among adults with Intellectual Disability (ID). Participants were 80 adults diagnosed with ID. Dependent variables were the composite score and domain scores of the Matson Evaluation of Drug Side-effects (MEDS), which is an instrument used to assess side effects. There were three levels of the independent variable: Group 1--those taking zero psychotropic medications, Group 2--those taking one psychotropic medication, and Group 3--those taking two psychotropic medications across different medication classes. There was a significant main effect regarding number of psychotropic medication classes prescribed. Further analysis revealed that four of the nine MEDS domains had significantly different mean scores for number of psychotropic medication classes. For the majority of MEDS domains, such as Central Nervous System-General, Parkinsonism/Dyskinesia, and Behavioral/Akathesia domains, participants in the no psychotropic medication group had significantly lower mean scores than those in the one and two psychotropic medication groups. Only two MEDS domains, Cardiovascular and Hematologic Effects as well as Skin, Allergies, and Temperature, were significantly different between participants taking one psychotropic medication as compared with two psychotropic medications from different classes. Implications of these findings and recommendations for future research are discussed. |
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Authors:
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Sara Mahan; Jodie Holloway; Jay W Bamburg; Julie A Hess; Jill C Fodstad; Johnny L Matson |
Publication Detail:
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Type: Journal Article; Multicenter Study Date: 2010-06-09 |
Journal Detail:
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Title: Research in developmental disabilities Volume: 31 ISSN: 1873-3379 ISO Abbreviation: Res Dev Disabil Publication Date: 2010 Nov-Dec |
Date Detail:
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Created Date: 2010-10-04 Completed Date: 2011-01-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8709782 Medline TA: Res Dev Disabil Country: United States |
Other Details:
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Languages: eng Pagination: 1561-9 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
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Louisiana State University, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Drug Therapy, Combination Female Humans Male Mental Retardation / drug therapy* Middle Aged Polypharmacy* Psychotropic Drugs / adverse effects* Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Psychotropic Drugs |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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