Document Detail

Exaggerated blood pressure response to dynamic exercise and risk of future hypertension.
MedLine Citation:
PMID:  9467632     Owner:  NLM     Status:  MEDLINE    
This study examined the association between an exaggerated blood pressure response to treadmill exercise and the risk of developing hypertension. Subjects were healthy normotensive men (n = 5386) who had a baseline graded maximal exercise test between 1971 and 1982, and completed a mailed follow-up questionnaire. At follow-up in 1986, cases (n = 151) reported physician diagnosed hypertension and controls (n = 201) reported normotension. Those who had developed hypertension at follow-up were more likely to have had an exaggerated blood pressure response to exercise (OR = 2.4, 1.4-4.3). In multiple logistic regression analysis an exaggerated response was significantly associated (OR = 3.0, 1.5-6.1) with future hypertension after controlling for sitting systolic and diastolic blood pressure, weight change from age 21 to follow-up, entry age, family history of hypertension, body mass index, treadmill time, alcohol consumption, and years of follow-up. These results suggest that an exaggerated blood pressure response to exercise is independently associated with increased risk of future hypertension, and therefore, may be an important factor in determining hypertension risk.
C E Matthews; R R Pate; K L Jackson; D S Ward; C A Macera; H W Kohl; S N Blair
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of clinical epidemiology     Volume:  51     ISSN:  0895-4356     ISO Abbreviation:  J Clin Epidemiol     Publication Date:  1998 Jan 
Date Detail:
Created Date:  1998-02-27     Completed Date:  1998-02-27     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8801383     Medline TA:  J Clin Epidemiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  29-35     Citation Subset:  IM    
School of Public Health, University of South Carolina, Columbia 29208, USA.
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MeSH Terms
Alcohol Drinking / adverse effects
Blood Pressure / physiology*
Body Mass Index
Case-Control Studies
Exercise Test*
Follow-Up Studies
Hypertension / etiology*
Logistic Models
Odds Ratio
Risk Factors
Sensitivity and Specificity
Weight Gain
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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