| Exacerbation of pemphigus after influenza vaccination. | |
| | |
MedLine Citation:
|
PMID: 18681883 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Pemphigus is a rare autoimmune disease characterized by flaccid blisters and erosions on skin and mucous epithelia. A critical event in its pathogenesis is production of antidesmoglein antibodies, which mediate the loss of intercellular adhesion in epithelia, leading to blister formation. Multiple environmental factors (ultraviolet radiation, trauma, drugs, infective agents) have been suggested as possible triggers of pemphigus. Occasionally, the disease has been reported to follow viral and bacterial vaccination. We describe a patient who experienced exacerbation of pemphigus shortly after administration of the influenza vaccination on two separate occasions. We review the literature, suggest possible explanations for a causal relationship, and discuss the administration of vaccination to these patients. |
| | |
Authors:
|
C De Simone; G Caldarola; M D'agostino; A Zampetti; P Amerio; C Feliciani |
Related Documents
:
|
21106443 - Effectiveness of inactivated influenza vaccine in children aged 9 months to 3 years: an... 7766913 - Influenza a outbreak in a nursing home: the value of early diagnosis and the use of ama... 19825923 - Modelling mitigation strategies for pandemic (h1n1) 2009. |
Publication Detail:
|
Type: Case Reports; Journal Article Date: 2008-08-02 |
Journal Detail:
|
Title: Clinical and experimental dermatology Volume: 33 ISSN: 1365-2230 ISO Abbreviation: Clin. Exp. Dermatol. Publication Date: 2008 Nov |
Date Detail:
|
Created Date: 2008-10-28 Completed Date: 2008-12-15 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7606847 Medline TA: Clin Exp Dermatol Country: England |
Other Details:
|
Languages: eng Pagination: 718-20 Citation Subset: IM |
Affiliation:
|
Department of Dermatology, Catholic University of the Sacred Heart, Rome, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Humans Immunocompromised Host* Influenza Vaccines / adverse effects* Male Middle Aged Mouth Mucosa / pathology Pemphigus / immunology*, pathology Skin / pathology |
| Chemical | |
Reg. No./Substance:
|
0/Influenza Vaccines |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Proteus syndrome complicated by multiple spinal meningiomas.
Next Document: Further experience of using azathioprine in the treatment of severe atopic dermatitis.