Document Detail


Exacerbation history is associated with medication and appointment adherence in MS.
MedLine Citation:
PMID:  21259038     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Disease-modifying treatments are designed to prevent exacerbations in multiple sclerosis (MS). To date, few studies have examined the relationship between disease activity and treatment adherence in MS. The primary aim of this study was to examine the association between disease activity (e.g., annualized relapse rates), medication adherence, and appointment adherence in relapsing-remitting MS. Retrospective exacerbation and appointment data were collected and used to predict prospective medication adherence. Results indicated that patients with higher annualized relapse rates missed fewer doses of medication and were less likely to miss appointments. Conversely, patients with relatively stable disease were more likely to demonstrate poor medication adherence and poor appointment adherence. Patients who missed more appointments also missed more doses of their disease modifying medication. Future studies may wish to examine clinical methods designed to improve immunotherapy adherence among patients who are in relatively symptom-free stages of relapsing-remitting MS.
Authors:
Laura M Hancock; Jared M Bruce; Sharon G Lynch
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-1-23
Journal Detail:
Title:  Journal of behavioral medicine     Volume:  -     ISSN:  1573-3521     ISO Abbreviation:  -     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-1-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7807105     Medline TA:  J Behav Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Psychology, University of Missouri-Kansas City, 4825 Troost Ave., Suite 124, Kansas City, MO, 64110, USA.
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