Document Detail

Exacerbation of adult-onset Still's disease, possibly related to elevation of serum tumor necrosis factor-alpha after etanercept administration.
MedLine Citation:
PMID:  21199457     Owner:  NLM     Status:  In-Data-Review    
Adult-onset Still's disease (AOSD) is a systemic inflammatory disease of unknown etiology. A 44-year-old male patient presented with AOSD complicated by macrophage activation syndrome after etanercept therapy. His serum tumor necrosis factor-α (TNF-α) level was increased dramatically after etanercept therapy. The clinical course of this case suggests that the increased TNF-α level by etanercept administration might cause macrophage activation syndrome in this case.
Kaichi Kaneko; Makoto Kaburaki; Sei Muraoka; Nahoko Tanaka; Tatsuhiro Yamamoto; Yoshie Kusunoki; Haruo Abe; Hirahito Endo; Shinichi Kawai
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of rheumatic diseases     Volume:  13     ISSN:  1756-185X     ISO Abbreviation:  Int J Rheum Dis     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2011-01-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101474930     Medline TA:  Int J Rheum Dis     Country:  England    
Other Details:
Languages:  eng     Pagination:  e67-9     Citation Subset:  IM    
Copyright Information:
© 2010 Asia Pacific League of Associations for Rheumatology and Blackwell Publishing Asia Pty Ltd.
Division of Rheumatology, Department of Internal Medicine (Omori), Toho University School of Medicine.
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