Document Detail

Ex vivo tissue-type independence in proton-resonance frequency shift MR thermometry.
MedLine Citation:
PMID:  9727949     Owner:  NLM     Status:  MEDLINE    
The temperature sensitivity of the proton-resonance frequency (PRF) has proven valuable for the monitoring of MR image-guided thermal coagulation therapy. However, there is significant inconsistency in reported values of the PRF-thermal coefficient, as measured from experiments encompassing a range of in vivo and ex vivo tissue types and experimental conditions. A method of calibrating the temperature dependence of the PRF is described and results are presented that indicate a tissue-type independence. To this end, other possible mechanisms for variations in the PRF-thermal coefficient are suggested, including physiological perturbations and volume magnetic susceptibility effects from geometry and orientation.
R D Peters; R S Hinks; R M Henkelman
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine     Volume:  40     ISSN:  0740-3194     ISO Abbreviation:  Magn Reson Med     Publication Date:  1998 Sep 
Date Detail:
Created Date:  1998-12-14     Completed Date:  1998-12-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8505245     Medline TA:  Magn Reson Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  454-9     Citation Subset:  IM    
Department of Medical Biophysics, University of Toronto, Sunnybrook Health Science Center, Ontario, Canada.
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MeSH Terms
Computer Systems
Hyperthermia, Induced / instrumentation*
Magnetic Resonance Imaging / instrumentation*
Magnetic Resonance Spectroscopy / instrumentation*
Phantoms, Imaging

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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