| Ex vivo leucocyte adhesion and protein adsorption on TiN. | |
| | |
MedLine Citation:
|
PMID: 8399968 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Titanium nitride (TiN) is regarded as a potential biomaterial for blood-contact applications. Its in vitro haemocompatibility has been evaluated already and gave promising results. The purpose of this study was to continue studying its 'biological' behaviour through an ex vivo evaluation. The material was a physical vapour deposition elaborated TiN coating and the phenomena observed were leucocyte adhesion and albumin and fibrinogen adsorption. These ex vivo results were compared with in vitro results obtained previously. Two reference medical grade silicone elastomer and three TiN arterio-arterial extra-corporeal circuits were tested. No leucocyte was retained by TiN, as in in vitro experiments; the ex vivo fibrinogen adsorbed quantity was higher and albumin adsorption was about the same in in vitro and in ex vivo situations. TiN can be considered as a suitable blood-contacting material. |
| | |
Authors:
|
I Dion; X Roques; N More; L Labrousse; J Caix; F Lefebvre; F Rouais; J Gautreau; C Baquey |
Related Documents
:
|
14737698 - Revision rhinoplasty. 10661028 - Preclinical evaluation of prototype products. 21685608 - 3,520 medication errors evaluated to assess the potential for it-based decision support. 10172408 - Congenital and acquired anophthalmia. 10975228 - The scope of hunter-gatherer ethnomedicine. 9465998 - Preconceptional sex selection: past, present, and future. |
Publication Detail:
|
Type: Comparative Study; In Vitro; Journal Article |
Journal Detail:
|
Title: Biomaterials Volume: 14 ISSN: 0142-9612 ISO Abbreviation: Biomaterials Publication Date: 1993 Jul |
Date Detail:
|
Created Date: 1993-11-24 Completed Date: 1993-11-24 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8100316 Medline TA: Biomaterials Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 712-9 Citation Subset: IM |
Affiliation:
|
INSERM U.306, Bordeaux, France. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adsorption Albumins / chemistry Animals Biocompatible Materials / chemistry* Cell Adhesion Dogs Erythrocytes / physiology Female Fibrinogen / chemistry Leukocytes / physiology* Microscopy, Electron, Scanning Platelet Adhesiveness Titanium / chemistry* |
| Chemical | |
Reg. No./Substance:
|
0/Albumins; 0/Biocompatible Materials; 11116-16-8/titanium nitride; 7440-32-6/Titanium; 9001-32-5/Fibrinogen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Synergistic inhibition of the calcification of glutaraldehyde pretreated bovine pericardium in a rat...
Next Document: Bioencapsulation: a biotechnological tool for biological life support for manned missions by the Eur...