| Ex-utero intrapartum therapy. | |
| | |
MedLine Citation:
|
PMID: 19683972 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The ex-utero intrapartum therapy (EXIT) procedure was designed to secure the airway at delivery in fetuses who had undergone tracheal occlusion for severe congenital diaphragmatic hernia. The EXIT was then adapted for deliveries where the airway may be difficult to secure, such as large neck masses or congenital high airway obstruction. Subsequently, use of EXIT has been extended to fetal anomalies where resuscitation may be compromised, including large thoracic masses, severe congenital diaphragmatic hernia, or pulmonary agenesis. The key to EXIT is preservation of uteroplacental blood flow and gas exchange, using inhalational agents to provide uterine relaxation, and maintenance of uterine volume by amnioinfusion and only partial exposure of the fetus. This provides time for procedures such as laryngoscopy, bronchoscopy, vascular access, resection of neck or lung masses, or cannulation for extracorporeal membrane circulation, in order to convert an emergent crisis to a controlled situation. |
| | |
Authors:
|
Kenneth W Liechty |
Publication Detail:
|
Type: Journal Article; Review Date: 2009-08-15 |
Journal Detail:
|
Title: Seminars in fetal & neonatal medicine Volume: 15 ISSN: 1878-0946 ISO Abbreviation: Semin Fetal Neonatal Med Publication Date: 2010 Feb |
Date Detail:
|
Created Date: 2010-02-04 Completed Date: 2010-04-23 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101240003 Medline TA: Semin Fetal Neonatal Med Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 34-9 Citation Subset: IM |
Copyright Information:
|
Copyright 2009. Published by Elsevier Ltd. |
Affiliation:
|
Center for Fetal Diagnosis and Treatment, Children's Hospital of Philadelphia, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA. Liechty@email.cho.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Airway Obstruction
/
congenital,
etiology,
surgery,
therapy* Balloon Dilatation Cystic Adenomatoid Malformation of Lung, Congenital / therapy Female Fetal Diseases / surgery, therapy* Head and Neck Neoplasms Hernia, Diaphragmatic / congenital, therapy Humans Infant, Newborn Intraoperative Care / methods* Mediastinal Neoplasms Organ Size Placental Circulation Pregnancy Prenatal Diagnosis* Trachea Tracheostomy Treatment Outcome Uterus / anatomy & histology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Neonatal arterial ischaemic stroke: obstetric issues.
Next Document: Abdominal wall gossypiboma.