Document Detail


Evolving appendicitis presenting as culture-negative peritonitis with minimal symptoms in a patient on continuous ambulatory peritoneal dialysis.
MedLine Citation:
PMID:  20662704     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Culture-negative peritonitis, which results from a variety of etiologies, such as problems in culture techniques, prior use of antibiotics, infection caused by unusual organisms, and noninfectious causes, accounts for up to 20% of cases of peritonitis in peritoneal dialysis patients and sometimes poses diagnostic and therapeutic dilemmas. A 62-year-old woman on continuous ambulatory peritoneal dialysis (CAPD) presented with minimal abdominal pain and a turbid dialysate. Under the impression of infectious peritonitis, empirical intraperitoneal (IP) antibiotic treatment was administered. All cultures from the effluent were negative, although the white blood cell count in the effluent was elevated. Despite initial clinical improvement and resolution of abdominal pain, mild fever persisted, even after removal of the CAPD catheter. The first CT scan before removal of the catheter demonstrated no evidence of intra-abdominal pathology, except for the possibility of peritonitis, but a follow-up CT scan after removal of the catheter demonstrated a perforated appendix with a peri-appendiceal abscess. The patient recovered completely after removal of the appendix and the abscess. This case suggests that a follow-up CT scan and/or surgical exploration should be considered to identify the intra-abdominal pathology in patients with culture-negative refractory peritonitis, even after removal of CAPD catheter.
Authors:
Yu-Ji Lee; A Jin Cho; Jung Eun Lee; Wooseong Huh; Yoon-Goo Kim; Ha Young Oh; Dae Joong Kim
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Renal failure     Volume:  32     ISSN:  1525-6049     ISO Abbreviation:  Ren Fail     Publication Date:  2010  
Date Detail:
Created Date:  2010-07-28     Completed Date:  2010-12-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8701128     Medline TA:  Ren Fail     Country:  England    
Other Details:
Languages:  eng     Pagination:  884-7     Citation Subset:  IM    
Affiliation:
Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
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MeSH Terms
Descriptor/Qualifier:
Appendicitis / diagnosis*,  microbiology
Enterobacter cloacae
Enterobacteriaceae Infections
False Negative Reactions
Female
Humans
Middle Aged
Peritoneal Dialysis, Continuous Ambulatory*
Peritonitis / diagnosis*,  microbiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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