Document Detail

Evolving concepts in Clostridium difficile colitis.
MedLine Citation:
PMID:  19765368     Owner:  NLM     Status:  MEDLINE    
Clostridium difficile infection (CDI) is the most important cause of nosocomial diarrhea. The emergence of a hypervirulent strain and other factors including antibiotic overuse contribute to the increasing incidence and severity of this potentially lethal infection. CDI has been reported in persons previously considered as low risk, such as young healthy persons without exposure to health care settings or antibiotics, peripartum women, and children. In patients with inflammatory bowel disease, the risk of C. difficile infection is even greater, with higher rates of hospitalization, bowel surgery, and mortality. With increasing incidence and severity of disease, the need for improved diagnostic, treatment, and infection control strategies cannot be overstated.
Naomi G Diggs; Christina M Surawicz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current gastroenterology reports     Volume:  11     ISSN:  1534-312X     ISO Abbreviation:  Curr Gastroenterol Rep     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-09-21     Completed Date:  2009-12-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888896     Medline TA:  Curr Gastroenterol Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  400-5     Citation Subset:  IM    
Department of Medicine, Division of Gastroenterology, University of Washington School of Medicine, Harborview Medical Center, Seattle, WA 98104, USA.
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MeSH Terms
Anti-Bacterial Agents / therapeutic use
Clostridium Infections / diagnosis*,  drug therapy,  epidemiology,  surgery
Colitis, Ulcerative / diagnosis
Crohn Disease / diagnosis
Cross Infection / diagnosis*,  drug therapy,  epidemiology,  surgery
Drug Therapy, Combination
Irritable Bowel Syndrome / diagnosis*,  drug therapy,  epidemiology,  surgery
Probiotics / therapeutic use
Recurrence / prevention & control
Severity of Illness Index
Treatment Outcome
Washington / epidemiology
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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