| Evolutionary perspectives on the fetal origins hypothesis. | |
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MedLine Citation:
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PMID: 15612045 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The fetal origins hypothesis, or Barker hypothesis, is both stimulating and challenging for evolutionary human biologists. While evidence of a correlation between conditions around the time of birth and later health outcomes has been presented before, the more recent evidence of a connection between fetal growth and chronic disease risk later in life has attracted considerable attention among epidemiologists and human biologists. Several themes that are fundamental to human biology emerge from an engagement with the fetal origins hypothesis. Among them are the tension between concepts of pathology, constraint, and adaptation; the importance of a life history perspective that embraces the notion of trade-offs; the question of environmental predictability; and the mechanisms of energy mobilization and allocation. Bringing the insights of evolutionary biology to bear on the fetal origins hypothesis illustrates the value of the field now known as evolutionary medicine. |
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Authors:
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Peter T Ellison |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: American journal of human biology : the official journal of the Human Biology Council Volume: 17 ISSN: 1042-0533 ISO Abbreviation: Am. J. Hum. Biol. Publication Date: 2005 Jan-Feb |
Date Detail:
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Created Date: 2004-12-27 Completed Date: 2005-05-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8915029 Medline TA: Am J Hum Biol Country: United States |
Other Details:
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Languages: eng Pagination: 113-8 Citation Subset: IM |
Copyright Information:
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(c) 2004 Wiley-Liss, Inc. |
Affiliation:
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Department of Anthropology, Harvard University, Cambridge, Massachusetts 02138, USA. AJHB@fas.harvard.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adaptation, Physiological* Animals Developmental Biology* Environment Evolution* Female Fetal Development / physiology* Humans Hypothalamo-Hypophyseal System / growth & development Neuronal Plasticity / physiology* Pituitary-Adrenal System / growth & development Pregnancy Prenatal Exposure Delayed Effects* |
| Comments/Corrections | |
Comment In:
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Am J Hum Biol. 2005 May-Jun;17(3):381-2
[PMID:
15849708
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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