Document Detail


Evolutionary inference for function-valued traits: Gaussian process regression on phylogenies.
MedLine Citation:
PMID:  23135249     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Biological data objects often have both of the following features: (i) they are functions rather than single numbers or vectors, and (ii) they are correlated owing to phylogenetic relationships. In this paper, we give a flexible statistical model for such data, by combining assumptions from phylogenetics with Gaussian processes. We describe its use as a non-parametric Bayesian prior distribution, both for prediction (placing posterior distributions on ancestral functions) and model selection (comparing rates of evolution across a phylogeny, or identifying the most likely phylogenies consistent with the observed data). Our work is integrative, extending the popular phylogenetic Brownian motion and Ornstein-Uhlenbeck models to functional data and Bayesian inference, and extending Gaussian process regression to phylogenies. We provide a brief illustration of the application of our method.
Authors:
Nick S Jones; John Moriarty
Related Documents :
17850199 - Pathological cerebral oscillatory activity in parkinson's disease: a critical review on...
20015259 - Measuring and monitoring illegal use of natural resources.
24130119 - Functional linear models for association analysis of quantitative traits.
18610259 - Erratum.
18846479 - Existing models and instruments for the selection of assistive technology in rehabilita...
22992489 - Data-driven analysis of analogous brain networks in monkeys and humans during natural v...
18781559 - A class comparison method with filtering-enhanced variable selection for high-dimension...
20371559 - A new classification system for shoulder instability.
20095029 - X-ray reconstruction of moving morphology (xromm): precision, accuracy and applications...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Royal Society, Interface / the Royal Society     Volume:  10     ISSN:  1742-5662     ISO Abbreviation:  J R Soc Interface     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2012-11-08     Completed Date:  2013-04-19     Revised Date:  2014-01-10    
Medline Journal Info:
Nlm Unique ID:  101217269     Medline TA:  J R Soc Interface     Country:  England    
Other Details:
Languages:  eng     Pagination:  20120616     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Models, Biological*
Phylogeny*
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Modelling emergence of oscillations in communicating bacteria: a structured approach from one to man...
Next Document:  Introducing a mixed-valent dirhodium(ii,iii) catalyst with increased stability in C-H amination.